|
|
| | 5-methoxy-1h-isoindole-1,3(2h)-dione Basic information | | Uses |
| Product Name: | 5-methoxy-1h-isoindole-1,3(2h)-dione | | Synonyms: | 5-methoxy-1h-isoindole-1,3(2h)-dione;4-MethoxyphthaliMide;5-methoxyisoindole-1,3-dione;1H-Isoindole-1,3(2H)-dione, 5-methoxy-;5-methoxyisoindoline-1,3-dione | | CAS: | 50727-04-3 | | MF: | C9H7NO3 | | MW: | 177.16 | | EINECS: | 1533716-785-6 | | Product Categories: | | | Mol File: | 50727-04-3.mol |  |
| | 5-methoxy-1h-isoindole-1,3(2h)-dione Chemical Properties |
| Melting point | 219 °C | | density | 1.346±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | pka | 9.84±0.20(Predicted) | | Appearance | White to off-white Solid |
| | 5-methoxy-1h-isoindole-1,3(2h)-dione Usage And Synthesis |
| Uses | 5-Methoxyisoindoline-1,3-dione is used as a reagent in the synthesis of KUP-1, a photoreactive and fluorescent pyrethroid, which can be used as a tool for photoaffinity labelling. | | Uses | 5-Methoxyisoindoline-1,3-dione is used as a reagent in the synthesis of KUP-1, a photoreactive and fluorescent pyrethroid, which can be used as a tool for photoaffinity labelling. | | Synthesis | General procedure for the synthesis of 5-methoxyisoindolane-1,3-dione from 5-methoxy-1-indanone: In a stainless steel autoclave with PTFE lining, 0.01 g of MnO2 catalyst, 0.5 mmol of 5-methoxy-1-indanone, 0.2 g of ammonia (25 wt%) and 2 g of chlorobenzene were added in sequence. The reaction temperature was raised to 110 °C by an automatic temperature controller, followed by the passage of 0.6 MPa oxygen, which was maintained at a constant pressure, and the reaction was continued for 4 hours. Upon completion of the reaction, the reaction mixture was analyzed by GC-MS and the yield of 5-methoxyisoindolidine-1,3-dione was measured to be 85%. | | References | [1] Patent: CN106278990, 2017, A. Location in patent: Paragraph 0013; 0017; 0018; 0020; 0023; 0028 |
| | 5-methoxy-1h-isoindole-1,3(2h)-dione Preparation Products And Raw materials |
|