| Company Name: |
BOC Sciences
|
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:OM-1700 CAS:2406276-78-4 Remarks:Reach out to us for more information about custom solutions.
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:OM-1700 CAS:2406276-78-4 Package:1removed
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OM-1700 manufacturers
- OM-1700
-
- $2785.00
-
2026-04-21
- CAS:2406276-78-4
- Purity:
- Supply Ability: 10g
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| | OM-1700 Basic information |
| Product Name: | OM-1700 | | Synonyms: | OM-1700;2-Pyridinecarboxamide, N-[trans-3-[5-(5-ethoxy-2-pyridinyl)-4-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl]cyclobutyl]- | | CAS: | 2406276-78-4 | | MF: | C25H23FN6O2 | | MW: | 458.49 | | EINECS: | | | Product Categories: | | | Mol File: | 2406276-78-4.mol |  |
| | OM-1700 Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | pka | 12.81±0.40(Predicted) |
| | OM-1700 Usage And Synthesis |
| Uses | OM-1700 is a potent tankyrase inhibitor with IC50s of 127 and 14 nM for tankyrase 1 and tankyrase 2, respectively. OM-1700 reduces cell growth in the colon cancer cell line COLO 320DM (GI50=650 nM)[1]. | | IC 50 | TNKS1: 127 nM (IC50); TNKS2: 14 nM (IC50) | | References | [1] Leenders RGG, et al. Development of a 1,2,4-Triazole-Based Lead Tankyrase Inhibitor: Part II. J Med Chem. 2021;64(24):17936-17949. DOI:10.1021/acs.jmedchem.1c01264 |
| | OM-1700 Preparation Products And Raw materials |
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