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| | N-(1-oxopropyl)-Glycine Basic information |
| | N-(1-oxopropyl)-Glycine Chemical Properties |
| Melting point | 126-127 °C | | Boiling point | 382.6±25.0 °C(Predicted) | | density | 1.174±0.06 g/cm3(Predicted) | | storage temp. | Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 3.60±0.10(Predicted) | | color | White to Off-White | | Major Application | clinical testing | | InChI | 1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9) | | InChIKey | WOMAZEJKVZLLFE-UHFFFAOYSA-N | | SMILES | OC(CNC(CC)=O)=O |
| WGK Germany | WGK 3 | | HazardClass | IRRITANT | | Storage Class | 11 - Combustible Solids |
| | N-(1-oxopropyl)-Glycine Usage And Synthesis |
| Uses | A metabolite of methylmalonic acid and propionic acid in children with methylmalonic acid and propionic acid metabolic disorders. | | Definition | ChEBI: A N-acylglycine obtained by formal condensation of the carboxy group of propionic acid with the amino group of glycine. | | Biological Activity | Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme th at catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase. |
| | N-(1-oxopropyl)-Glycine Preparation Products And Raw materials |
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