| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Axl-IN-9
CAS:2487649-73-8
Package:1removed
|
1H-Pyrazole-4-carboxamide, N-[4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- manufacturers
- Axl-IN-9
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- $2785.00
-
2026-05-11
- CAS:2487649-73-8
- Purity:
- Supply Ability: 10g
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| | 1H-Pyrazole-4-carboxamide, N-[4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- Basic information |
| | 1H-Pyrazole-4-carboxamide, N-[4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) | | pka | 12.33±0.70(Predicted) |
| | 1H-Pyrazole-4-carboxamide, N-[4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- Usage And Synthesis |
| Uses | Axl-IN-9 (Example 10) is a potent AXL inhibitor, with an IC50 of 26 nM. Axl-IN-9 has excellent transmembrane properties. Axl-IN-9 exhibits excellent pharmacokinetic properties in an animal body. Axl-IN-9 can be used for the research of proliferative diseases, autoimmune diseases, allergic diseases, inflammatory diseases, transplant rejection, cancer, or other diseases in mammals[1]. | | IC 50 | Axl | | References | [1] Xi Ning. Substituted heteroaryl compound, composition of same, and uses thereof. WO2020182188A1. |
| | 1H-Pyrazole-4-carboxamide, N-[4-(4-amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)phenyl]-2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl- Preparation Products And Raw materials |
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