CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID

CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Suppliers list
Company Name: BOC Sciences
Tel: +1-631-485-4226
Email: inquiry@bocsci.com
Products Intro: Product Name:CGS 19755
CAS:110347-85-8
Remarks:Please reach out to us for more information about custom solutions.
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Selfotel；CGS 19755;LY-272541
CAS:110347-85-8
Package:10 mg；100 mg；2 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Labnetwork lnc.
Tel: +86-27-50766799 +8618062016861
Email: contact@labnetwork.com
Products Intro: Product Name:(2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid
CAS:110347-85-8
Purity:95% Package:1kg+
Company Name: Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel: +86-057181025280; +8617767106207
Email: sales@molcore.com
Products Intro: Product Name:Selfotel
CAS:110347-85-8
Purity:98% Min. Remarks:MC34325
Company Name: NANJING YINGWEN BIOTECHNOLOGY CO LTD
Tel: +8613382787392
Email: sales@aeechem.com
Products Intro: CAS:110347-85-8
Purity:98%
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Basic information
Product Name:CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID
Synonyms:CGS 19755;CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID;CGS-19755 \ POTENT COMPETITIVE NMDA RECE;cis-4-[Phosphomethyl]-piperidine-2-carboxylicacid;LY-272541;CPDD 0027;4-(phosphonomethyl)-2-piperidinecarboxylic acid;CIS-(2S,4R)-4-(phosphonomethyl)piperidine-2-carboxylic acid
CAS:110347-85-8
MF:C7H14NO5P
MW:223.16
EINECS:
Product Categories:Glutamate receptor
Mol File:110347-85-8.mol
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Structure
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Chemical Properties
Melting point 290-292 °C
Boiling point 508.6±60.0 °C(Predicted)
density 1.440±0.06 g/cm3(Predicted)
storage temp. Store at RT
solubility H2O: soluble
form solid
pka2.29±0.10(Predicted)
color white
Water Solubility Soluble to 25 mM in water
Safety Information
WGK Germany 3
MSDS Information
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Usage And Synthesis
UsesCGS 19755 is a potent and competitive NMDA antagonist.
DefinitionChEBI: Selfotel is a non-proteinogenic alpha-amino acid.
Biological ActivityPotent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective. Also available as part of the Mixed NMDA Receptor Tocriset™ .
in vivo

Selfotel (CGS 19755) administered p.o. by gavage has little or no effect in these test procedures. In an experimental model of anxiety in rats[1].
Selfotel (CGS 19755) significantly increases conflict responding within a relatively narrow dose range (minimum effective dose, 1.73 mg/kg i.p.)[1].
Selfotel (CGS 19755) blocks the harmaline-induced increase in cerebellar cyclic GMP levels at a dose of 4 mg/kg i.p. with duration of action exceeding 2 hr[2].
Selfotel (CGS 19755) inhibits convulsions elicited by maximal electroshock in rat (ED50 = 3.8 mg/kg i.p. 1 hr after administration) and in mouse (ED50 = 2.0 mg/kg i.p. 0.5 hr after administration)[2].

storageStore at RT
CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID Preparation Products And Raw materials
Tag:CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID(110347-85-8) Related Product Information
4-AMINOBUTYLPHOSPHONIC ACID L-AP5 5-PHOSPHONOPENTANOIC ACID DL-2-AMINO-5-PHOSPHONOPENTANOIC ACID CIS-4-[PHOSPHONOMETHYL]-PIPERIDINE-2-CARBOXYLIC ACID