| Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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13636370518 |
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shyysw007@163.com |
| Products Intro: |
Product Name:Glycohyocholic acid
CAS:32747-08-3
Purity:98% Package:1mg Remarks:B74542
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Glycohyocholic acid manufacturers
- Glycohyocholic acid
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- $1.00
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2024-08-02
- CAS:32747-08-3
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20T
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| | Glycohyocholic acid Basic information |
| Product Name: | Glycohyocholic acid | | Synonyms: | N-(24-Oxo-3α,6α,7α-trihydroxy-5β-cholan-24-yl)glycine;N-(3α,6α,7α-Trihydroxy-24-oxo-5β-cholan-24-yl)glycine;Glycohyocholic acid;2-[[(4R)-4-[(3R,5R,6R,7S,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]acetic acid;Glycohyocholic acid (GHCA);Glycine, N-[(3α,5β,6α,7α)-3,6,7-trihydroxy-24-oxocholan-24-yl]-;5β-CHOLANIC ACID-3α, 6α, 7α-TRIOL N-(CARBOXYMETHYL)-AMIDE SODIUM SALT;Hyocholic acid-glycine conjugate | | CAS: | 32747-08-3 | | MF: | C26H43NO6 | | MW: | 465.63 | | EINECS: | | | Product Categories: | | | Mol File: | 32747-08-3.mol |  |
| | Glycohyocholic acid Chemical Properties |
| Boiling point | 673.4±55.0 °C(Predicted) | | density | 1.213±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml | | form | A crystalline solid | | pka | 3.58±0.10(Predicted) | | color | Off-white to light yellow | | InChIKey | ZQYUKJFJPJDMMR-ZDWCHQGWSA-N | | SMILES | [H][C@@]12[C@]([C@](CC[C@@H](O)C3)(C)[C@]3([H])[C@@H](O)[C@H]2O)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)CCC(NCC(O)=O)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Glycohyocholic acid Usage And Synthesis |
| Description | Glycohyocholic acid (GHCA) is a glycine-conjugated form of the primary bile acid hyocholic acid . GHCA is upregulated 6.6-fold in the serum of patients with cirrhosis induced by hepatitis C virus (HCV) compared to healthy controls. Plasma levels of GHCA increase in patients who are no longer diabetic following gastric bypass surgery. | | Uses | Glycohyocholic Acid is a bile salt. | | Definition | ChEBI: Glycohyocholic acid is a bile acid glycine conjugate having hyocholic acid as the bile acid component. It has a role as a human metabolite. It is functionally related to a hyocholic acid. It is a conjugate acid of a glycohyocholate. | | References | [1] LINING GUO. Plasma metabolomic profiles enhance precision medicine for volunteers of normal health.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2015: E4901-10. DOI: 10.1073/pnas.1508425112
[2] ASEM I. FITIAN. Integrated metabolomic profiling of hepatocellular carcinoma in hepatitis C cirrhosis through GC/MS and UPLC/MS-MS[J]. Liver International, 2014, 34 9: 1428-1444. DOI: 10.1111/liv.12541
[3] HAOYONG YU. Chenodeoxycholic Acid as a Potential Prognostic Marker for Roux-en-Y Gastric Bypass in Chinese Obese Patients.[J]. Journal of Clinical Endocrinology & Metabolism, 2015, 100 11: 4222-4230. DOI: 10.1210/jc.2015-2884 |
| | Glycohyocholic acid Preparation Products And Raw materials |
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