| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:KCN1
CAS:927823-01-6
Remarks:Reach out to us for more information about custom solutions.
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:KCN1
CAS:927823-01-6
Package:1removed
|
KCN1 manufacturers
- KCN1
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- $2500.00
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2026-04-21
- CAS:927823-01-6
- Purity:
- Supply Ability: 10g
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| Product Name: | KCN1 | | Synonyms: | KCN1;Benzenesulfonamide, N-[(2,2-dimethyl-2H-1-benzopyran-6-yl)methyl]-3,4-dimethoxy-N-phenyl-;KCNA10 | | CAS: | 927823-01-6 | | MF: | C26H27NO5S | | MW: | 465.56 | | EINECS: | | | Product Categories: | | | Mol File: | 927823-01-6.mol |  |
| Uses | KCN1 is a p300/HIF-1α interaction inhibitor. KCN1 inhibits HIF transcriptional activity by binding to the CH1 domain of p300 and preventing the p300/HIF-1α assembly. KCN1 exerts antitumor activities through cell cycle arrest[1][2]. | | IC 50 | p300 | | References | [1] Shi Q, et al. Binding Model for the Interaction of Anticancer Arylsulfonamides with the p300 Transcription Cofactor. ACS Med Chem Lett. 2012 Jun 21;3(8):620-5. DOI:10.1021/ml300042k
[2] Wang W, et al. KCN1, a novel synthetic sulfonamide anticancer agent: in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. PLoS One. 2012;7(9):e44883. DOI:10.1371/journal.pone.0044883 |
| | KCN1 Preparation Products And Raw materials |
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