| Company Name: |
Shanghai Raise Chemical Technology Co.,Ltd
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| Tel: |
15026594951 |
| Email: |
rs@raise-chem.com |
| Products Intro: |
Product Name:tert-butyl(3-hydroxyphenethyl)carbamate
CAS:129150-68-1
Purity:97% HPLC Package:1g；5g；10g
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| | tert-butyl(3-hydroxyphenethyl)carbamate Basic information |
| Product Name: | tert-butyl(3-hydroxyphenethyl)carbamate | | Synonyms: | tert-butyl(3-hydroxyphenethyl)carbamate;N-(t-butoxycarbonyl)-2-(3-hydroxyphenyl)-ethylamine;3-[2-(Boc-amino)ethyl]phenol;Carbamic acid, N-[2-(3-hydroxyphenyl)ethyl]-, 1,1-dimethylethyl ester;tert-butyl N-[2-(3-hydroxyphenyl)ethyl]carbamate;tert-Butyl N-(3-hydroxyphenethyl)carbamate | | CAS: | 129150-68-1 | | MF: | C13H19NO3 | | MW: | 237.29 | | EINECS: | | | Product Categories: | | | Mol File: | 129150-68-1.mol |  |
| | tert-butyl(3-hydroxyphenethyl)carbamate Chemical Properties |
| Boiling point | 397.1±25.0 °C(Predicted) | | density | 1.100±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 9.98±0.10(Predicted) | | Appearance | Off-white to light yellow Solid |
| | tert-butyl(3-hydroxyphenethyl)carbamate Usage And Synthesis |
| Synthesis | Step B: Synthesis of tert-butyl [2-(3-hydroxyphenyl)ethyl]carbamate; 1 g of 10% Pd/C catalyst was added to a 100 mL ethanol solution containing 13 g (0.039 mol) of tert-butyl [2-(3-benzyloxyphenyl)ethyl]carbamate. The reaction mixture was subjected to hydrogenation at 40 psi hydrogen pressure overnight. Upon completion of the reaction, the catalyst was removed by filtration and washed with ethanol. Subsequently, the solvent was evaporated under reduced pressure to give 9.4 g of tert-butyl 3-hydroxyphenethylcarbamate as a colorless oil in quantitative yield.1H-NMR (CDCl3) δ: 7.22-7.12 (m, 1H); 6.78-6.66 (m, 3H); 4.56 (bs, 1H); 3.42-3.30 (m, 2H); 2.74 (t, 2H); 1.44 (s, 9H). | | References | [1] Patent: WO2007/71311, 2007, A1. Location in patent: Page/Page column 55-56
[2] Patent: WO2014/95920, 2014, A1. Location in patent: Page/Page column 70
[3] Journal of Organic Chemistry, 1990, vol. 55, # 24, p. 6000 - 6017
[4] Patent: WO2009/68177, 2009, A1. Location in patent: Page/Page column 39
[5] Patent: US2010/210631, 2010, A1. Location in patent: Page/Page column 14 |
| | tert-butyl(3-hydroxyphenethyl)carbamate Preparation Products And Raw materials |
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