BACE1-IN-1 manufacturers
- BACE1-IN-1
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- $1650.00
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2026-04-21
- CAS:1310347-50-2
- Purity:
- Supply Ability: 10g
- BACE1-IN-1
-
- $1650.00
-
2025-10-28
- CAS:1310347-50-2
- Purity:
- Supply Ability: 10g
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| | BACE1-IN-1 Basic information |
| Product Name: | BACE1-IN-1 | | Synonyms: | BACE1-IN-1;2-Pyridinecarboxamide, N-[3-[(4R)-2-amino-5,5-difluoro-5,6-dihydro-4-methyl-4H-1,3-oxazin-4-yl]-4-fluorophenyl]-5-cyano-;BACE-1-IN-1,BACE1 IN 1,BACE1IN1 | | CAS: | 1310347-50-2 | | MF: | C18H14F3N5O2 | | MW: | 389.33 | | EINECS: | | | Product Categories: | | | Mol File: | 1310347-50-2.mol |  |
| | BACE1-IN-1 Chemical Properties |
| density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | pka | 9.95±0.70(Predicted) | | color | White to off-white |
| | BACE1-IN-1 Usage And Synthesis |
| Uses | BACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. | | IC 50 | BACE1 | | References | [1] Hilpert H, et al. β-Secretase (BACE1) inhibitors with high in vivo efficacy suitable for clinical evaluation in Alzheimer's disease. J Med Chem. 2013 May 23;56(10):3980-95. DOI:10.1021/jm400225m |
| | BACE1-IN-1 Preparation Products And Raw materials |
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