- Deslanoside
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2025-06-20
- CAS:17598-65-1
- Min. Order: 25KG
- Purity: 0.99
- Supply Ability: 5000kg/month
- Deslanoside
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- $3.00
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2020-01-19
- CAS:17598-65-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 1kg,5kg,50kg
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| | Deslanoside Basic information |
| Product Name: | Deslanoside | | Synonyms: | cedilanidd;deacetyl-lanatoside;desacetyllanatosidec;descetyldigilanidec;deslanatoside;sediranido;Deslanoside (JP14/USP);Card-20(22)-enolide, 3-[(O-β-D-glucopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-(1→4)-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-, (3β,5β,12β)- | | CAS: | 17598-65-1 | | MF: | C47H74O19 | | MW: | 943.08 | | EINECS: | 241-568-1 | | Product Categories: | Cardioglycosides & Glycosides | | Mol File: | 17598-65-1.mol |  |
| | Deslanoside Chemical Properties |
| Melting point | 220-235°C | | alpha | D20 +12° (c = 1.084 in 75% alc) | | Boiling point | 732.1°C (rough estimate) | | density | 1.1255 (rough estimate) | | refractive index | 1.6500 (estimate) | | storage temp. | 2-8°C | | solubility | DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml | | form | Solid | | pka | 12.89±0.70(Predicted) | | color | White to off-white | | Major Application | pharmaceutical (small molecule) | | InChIKey | OBATZBGFDSVCJD-LALPQLPRSA-N | | CAS DataBase Reference | 17598-65-1(CAS DataBase Reference) |
| Risk Statements | 23/25-33 | | Safety Statements | 1-22-45 | | RIDADR | 2811 | | WGK Germany | WGK 3 | | HS Code | 2938900000 | | Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2
very toxic hazardous materials | | Hazard Classifications | Acute Tox. 3 Inhalation
Acute Tox. 3 Oral
STOT RE 2 | | Toxicity | cat,LD50,intravenous,230ug/kg (0.23mg/kg),"Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963Vol. -, Pg. 190, 1963. |
| | Deslanoside Usage And Synthesis |
| Chemical Properties | Solution S is clear (2.2.1) and colourless (2.2.2, Method II). | | Uses | Cardiotonic. | | Definition | ChEBI: Deslanoside is a cardenolide glycoside that is lanatoside C with the acetoxy group replaced by a hydroxy group. It has a role as an anti-arrhythmia drug, a cardiotonic drug, a metabolite and an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor. It is a 14beta-hydroxy steroid, a 12beta-hydroxy steroid, a cardenolide glycoside and a tetrasaccharide derivative. | | Brand name | Cedilanid-D (Novartis). | | General Description | Deslanoside is a white crystalline powder; odourless, with a bitter taste; hygroscopic. It is slightly soluble in methanol, very slightly soluble in ethanol, and practically insoluble in water or chloroform. | | Biological Activity | Deslanoside is a cardiac glycoside that has been found in D. lanata.[1] It induces ventricular tachycardia in anesthetized dogs when administered intravenously at a dose of 0.18 mg/kg.[2] Formulations containing deslanoside have been used in the treatment of congestive heart failure and cardiac arrythmias.? | | References | [1] Koren, G., and Soldin, S.J. Cardiac glycosides. Clin. Lab. Med. 7(3), 587-606 (1987).
[2] Ghani, M.F., and Smith, J.R. The effectiveness of magnesium chloride in the treatment of ventricular tachyarrhythmias due to digitalis intoxication. Am. Heart J. 88(5), 621-626 (1974).
[3] MALGORZATA KLYS Adam G. Determination of deslanoside in antemortem and postmortem specimens. Unusual case report[J]. Forensic science international, 1990, 45 3: Pages 231-238. DOI:10.1016/0379-0738(90)90179-3. |
| | Deslanoside Preparation Products And Raw materials |
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