莰菲醇-3-O-蕓香糖苷
| 中文名稱 | 莰菲醇-3-O-蕓香糖苷 |
|---|---|
| 中文同義詞 | 山柰酚-3-O-蕓香糖苷(煙花苷,莰菲醇-3-O-蕓香糖苷,莰非醇-3-O-蕓香糖苷);山柰酚-3-O-蕓香糖苷;莰菲醇-3-O-蕓香糖苷;莰非醇-3-O-蕓香糖苷;山柰酚-3-O-蕓香糖苷(標(biāo)準(zhǔn)品);煙花苷;山柰酚-3-O-蕓香糖苷, 來源于紅花;煙花苷,莰菲醇-3-O-蕓香糖苷,莰非醇-3-O-蕓香糖苷 |
| 英文名稱 | KAEMPFEROL-3-O-RUTINOSIDE |
| 英文同義詞 | 3,4′,5,7-Tetrahydroxyflavone 3-rhamnoglucoside;KaeMpferol-3-O-rutinosid, froM CarthaMus tinctorius;KAEMPFEROL-3-O-RUTINOSIDE;Kaempfeol-3-O-rutinoside;KAEMPFEROL-3-O-RUTINOSIDE WITH HPLC;KAEMPFEROL-3-RUTINOSIDE hplc;3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(4-hydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one;3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
| CAS號 | 17650-84-9 |
| 分子式 | C27H30O15 |
| 分子量 | 594.52 |
| EINECS號 | |
| 相關(guān)類別 | 對照品;標(biāo)準(zhǔn)品;植物提取物;中藥對照品;植提標(biāo)準(zhǔn)品;類黃酮;化學(xué)連接;Tetra-substituted Flavones;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;標(biāo)準(zhǔn)品-中藥標(biāo)準(zhǔn)品;對照品-中藥對照品;黃酮;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品;標(biāo)準(zhǔn)品，對照品;黃金產(chǎn)品 |
| Mol文件 | 17650-84-9.mol |
| 結(jié)構(gòu)式 |  |
莰菲醇-3-O-蕓香糖苷 性質(zhì)
| 熔點 | 200°C (dec.) |
|---|---|
| 沸點 | 941.7±65.0 °C(Predicted) |
| 密度 | 1.76 |
| 儲存條件 | Inert atmosphere,Store in freezer, under -20°C |
| 溶解度 | 可溶于氯仿（少許）、DMSO（少許）、甲醇（少許） |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 6.20±0.40(Predicted) |
| 顏色 | 灰白色至黃色 |
| 生物來源 | plant (Clematis cultivar) |
| 穩(wěn)定性 | 吸濕性 |
| 化妝品成分功效 | 抗氧化劑 皮膚調(diào)理 - 潤膚劑 皮膚保護(hù) |
| InChIKey | RTATXGUCZHCSNG-FVJKAJKWNA-N |
| SMILES | C1(O[C@H]2[C@H](O)[C@H]([C@H](O)[C@@H](CO[C@@H]3O[C@H]([C@H](O)[C@@H](O)[C@H]3O)C)O2)O)C(=O)C2=C(C=C(O)C=C2O)OC=1C1C=CC(O)=CC=1 |&1:2,3,5,6,8,11,13,14,16,18,r| |
| Target | Value |
|
p-JAK2
() | |
|
p-STAT3
() | |
|
caspase-3
() | |
|
Bax
() | |
|
Bcl-2
() |
For primarily cultured neurons suffered 2 h hypoxia followed by 24 h reoxygenation, nicotiflorin significantly attenuates cell death and reduces LDH release. Morphological observation also directly confirms its protective effect on neuron. After total 4 h hypoxia and 12 h reoxygenation, eNOS activity, mRNA and protein levels in the primarily cultured rat cerebral blood vessel endothelial cells treated with nicotiflorin (25-100 g/mL) 2 h after onset of hypoxia are significantly higher than eNOS activity, mRNA and protein levels in the pure H-R cells and also higher than eNOS activity, mRNA and protein levels in cells cultured under normoxic conditions.
At doses of 2.5, 5 and 10 mg/kg, nicotiflorin administered immediately after the onset of ischemia markedly reduces brain infarct volume and neurological deficits. Nicotiflorin (2.5-10 mg/kg) administered after onset of ischemia markedly reduces brain infarct volume by 24.5-63.2% and neurological deficits.
藥理藥效:降血脂、善癡呆癥狀和記憶保護(hù)
安全信息
| 危險品標(biāo)志 | Xn |
|---|---|
| 危險類別碼 | 22 |
| 安全說明 | 22-45-24/25 |
| WGK Germany | 3 |
| 海關(guān)編碼 | 29389090 |
| 存儲類別 | 11 - 可燃固體 |
| 更新日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/07/06 | S3267 | 莰菲醇-3-O-蕓香糖苷 Kaempferol-3-O-rutinoside | 17650-84-9 | 1mg | 1170.54元 |
| 2026/07/06 | S3267 | 莰菲醇-3-O-蕓香糖苷 Kaempferol-3-O-rutinoside | 17650-84-9 | 5mg | 2596.23元 |