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| | Z-GLY-GLY-LEU-AMC Basic information |
| Product Name: | Z-GLY-GLY-LEU-AMC | | Synonyms: | PROTEASOME SUBSTRATE V, FLUOROGENIC;Z-GLY-GLY-LEU-AMC;Z-GGL-AMC;Carbobenzoxy-Gly-Gly-Leu-7-amido-4-methylcoumarin, benzyloxycarbonyl-glycyl-glycyl-leucyl-7-amido-4-methylcoumarin;Proteasome Substrate;7-(N-benzyloxycarbonylglycyl-glycyl-leucyl)amino-4-methylcoumarin;7-(Nα-benzyloxycarbonyl-glycylglycyl-L-leucyl)amino-4-methylcoumarin;L-Leucinamide, N-[(phenylmethoxy)carbonyl]glycylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- | | CAS: | 97792-39-7 | | MF: | C28H32N4O7 | | MW: | 536.58 | | EINECS: | | | Product Categories: | Proteasome substrate V | | Mol File: | 97792-39-7.mol |  |
| | Z-GLY-GLY-LEU-AMC Chemical Properties |
| Boiling point | 877.646±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.281±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -15°C | | form | White powder. | | pka | 11.028±0.46(predicted) | | Sequence | {Cbz}-Gly-Gly-Leu-{AMC} |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Z-GLY-GLY-LEU-AMC Usage And Synthesis |
| Uses | Z-GGL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 20S proteasome. It is a sensitive fluorogenic substrate for subtilisins BPN'' and Carlsberg. | | Biological Activity | Z-Gly-Gly-Leu-7-amido-4-methylcoumarin (Z-Gly-Gly-Leu-AMC) is a fluorogenic peptide th at is used in analysis of protease and peptidase activity of proteasomes. Z-GGL-AMC has been noted as a particular substrate for chymotrypsin-like activity. It has low solubility and precipitates at 100μM. |
| | Z-GLY-GLY-LEU-AMC Preparation Products And Raw materials |
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