- ISOPROPYL GLYCOLATE
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- $1.00
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2020-01-05
- CAS:623-61-0
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100KG
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| | ISOPROPYL GLYCOLATE Basic information |
| Product Name: | ISOPROPYL GLYCOLATE | | Synonyms: | Propan-2-yl 2-hydroxyacetate;2-hydroxyacetic acid isopropyl ester;propan-2-yl 2-hydroxyethanoate;2-hydroxy-3-Methylbutanoate;isopropyl glycolat;ISOPROPYL GLYCOLATE;Glycolic acid isopropyl ester;Hydroxyacetic acid isopropyl ester | | CAS: | 623-61-0 | | MF: | C5H10O3 | | MW: | 118.13 | | EINECS: | 210-804-5 | | Product Categories: | | | Mol File: | 623-61-0.mol |  |
| | ISOPROPYL GLYCOLATE Chemical Properties |
| Boiling point | 159.3±8.0 °C(Predicted) | | density | 1.050±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 13.21±0.10(Predicted) | | Appearance | Colorless to light yellow Liquid | | Water Solubility | Slightly soluble in water. |
| Provider | Language |
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ALFA
| English |
| | ISOPROPYL GLYCOLATE Usage And Synthesis |
| Uses | Isopropyl glycolate is used as pharmaceutical intermediate. | | Synthesis | The general procedure for the synthesis of isopropyl hydroxyacetate from dimethyl oxalate was as follows: first, the hydrogenation of the ester compound was carried out using bipyridyltetraethylruthenium complex 5 as a catalyst. The specific reaction conditions were as follows: the ratio of substrate to catalyst (S/C) was 1000, the amount of substrate was 3.0 mmol, the amount of catalyst 5 was 3.0 μmol, the solvent was 3.0 mL of isopropanol (iPrOH), and 0.3 mmol of sodium methanol (NaOMe) was added as the base, and the hydrogen pressure was 5 MPa, and the temperature of the reaction was 25 ℃. The reaction results are detailed in Table 2, which lists the hydrogenation results of other ester compounds under the same conditions. | | References | [1] Patent: CN103980317, 2017, B. Location in patent: Paragraph 0098; 0099; 0100; 0102; 0104 |
| | ISOPROPYL GLYCOLATE Preparation Products And Raw materials |
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