Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester

Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Suppliers list
Company Name: Beijing Jin Ming Biotechnology Co., Ltd.  
Tel: 010-60605840 18892239720
Email: psaitong@jm-bio.com
Products Intro: Product Name:Cyclooctyne-O-amido-PEG3-PFP ester
CAS:2101206-33-9
Package:100mg;250mg;500mg
Company Name: Henan Mengtai Pharmaceutical Technology Co., Ltd  
Tel: 17634413542 17634854698;
Email: 1959525201@qq.com
Products Intro: Product Name:Cyclooctyne-O-amido-PEG3-PFP ester
CAS:2101206-33-9
Purity:98% HPLC
Company Name: MedChemExpress  
Tel: 021-58955995
Email: sales@medchemexpress.com
Products Intro: Product Name:Cyclooctyne-O-amido-PEG3-PFP ester
CAS:2101206-33-9
Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Basic information
Product Name:Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
Synonyms:Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester;Cyclooctyne-O-amido-PEG3-PFP ester
CAS:2101206-33-9
MF:C25H30F5NO7
MW:551.5
EINECS:
Product Categories:
Mol File:2101206-33-9.mol
Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Structure
Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Chemical Properties
Boiling point 640.5±55.0 °C(Predicted)
density 1.31±0.1 g/cm3(Predicted)
pka14.02±0.46(Predicted)
Safety Information
MSDS Information
Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Usage And Synthesis
UsesCyclooctyne-O-amido-PEG3-PFP ester is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Cyclooctyne-O-amido-PEG3-PFP ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50Non-cleavable Linker
References[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Preparation Products And Raw materials
Tag:Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester(2101206-33-9) Related Product Information
Propanoic acid, 3-[2-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester Propanoic acid, 3-[2-[2-[[2-(2-cyclooctyn-1-yloxy)acetyl]amino]ethoxy]ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester