| Company Name: |
LGC Science (Shanghai) Ltd.
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| Tel: |
17717235263 |
| Email: |
offer.de@lgcgroup.com |
| Products Intro: |
Product Name:Pregabalin Isobutyl Ester Hydrochloride CAS:1239692-15-9 Purity:99%, 有含量賦值, 檢測方法: HPLC/H-NMR/MS/IR等(具體純度詳見COA,官網(wǎng)可下 Package:25mg Remarks:MM1376.16
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| | Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- Basic information |
| | Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- Chemical Properties |
| | Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- Usage And Synthesis |
| Synthesis | This impurity Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- was quantitatively synthesized in the form of hydrochloride salt by the reaction of Pregabalin with thionyl chloride in the presence of isobutanol[1].

| | References | [1] Sripathi, S., Somesetti, N. R., Veeramalla, R., Challa, N. R., Peddi, S., Karnati, V. R. (2010). Synthesis and characterization of impurities of an anticonvulsant drug, Pregabalin. Arkivoc, 2010 1. https://doi.org/10.3998/ARK.5550190.0011.A22
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| | Hexanoic acid, 3-(aminomethyl)-5-methyl-, 2-methylpropyl ester, hydrochloride (1:1), (3S)- Preparation Products And Raw materials |
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