| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
4008200310 15002144251 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:ICI 153110
CAS:87164-90-7
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
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ICI 153110 manufacturers
- ICI 153110
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- $1520.00
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2026-04-20
- CAS:87164-90-7
- Purity:
- Supply Ability: 10g
- ICI 153110
-
- $1520.00
-
2025-08-22
- CAS:87164-90-7
- Purity:
- Supply Ability: 10g
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| | ICI 153110 Basic information |
| Product Name: | ICI 153110 | | Synonyms: | ICI 153110;4,5-Dihydro-6-[(E)-2-(4-pyridinyl)ethenyl]-2H-pyridazin-3-one;3(2H)-Pyridazinone, 4,5-dihydro-6-[(1E)-2-(4-pyridinyl)ethenyl]-;(E)-4,5-Dihydro-6-(2-(4-pyridinyl)ethenyl)-3(2H)-pyridazinone | | CAS: | 87164-90-7 | | MF: | C11H11N3O | | MW: | 201.22 | | EINECS: | | | Product Categories: | | | Mol File: | 87164-90-7.mol |  |
| | ICI 153110 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | ICI 153110 Usage And Synthesis |
| Uses | ICI 153110 is an orally active phosphodiesterase inhibitor with both vasodilating and inotropic properties which is designed for the treatment of congestive cardiac failure. | | in vivo | ICI 153110 is an orally active phosphodiesterase inhibitor with both vasodilating and inotropic properties which is designed for the treatment of congestive cardiac failure. Fourteen animals have died as a direct or indirect consequence of ICI 153110 administration in the high-dose main test and reversibility groups. In the female rat dosed at 10 mg/kg/day ICI 153110 a mild focal arteritis is characterized by a predominantly and diffusely adventitial infiltration of mixed cells and early formation of fibrous tissue. The two rats dosed at 250 mg/kg/day ICI 153110 die prematurely from intratracheal intubation of dosing solution. Arteries from two further animals (dosed at 5 and 250 mg/kg/day ICI 153110) show minimal focal arteritis with medial necrosis, and medial and adventitial inflammation[1]. | | References | [1] Westwood FR, et al. Pathologic changes in blood vessels following administration of an inotropic vasodilator (ICI 153,110) to the rat. Fundam Appl Toxicol. 1990 May;14(4):797-809. DOI:10.1016/0272-0590(90)90304-3 |
| | ICI 153110 Preparation Products And Raw materials |
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