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Product Name:Isoegomaketone
CAS:34348-59-9
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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Product Name:ISOEGOMAKETONE
CAS:34348-59-9
Purity:0.98 Package:1kg；5kg；25kg…...
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Product Name:(2E)-1-(3-Furyl)-4-methyl-2-penten-1-one
CAS:34348-59-9
Purity:98% Package:0.1ml Remarks:B29906
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Product Name:isoegomaketone
CAS:34348-59-9
Purity:HPLC>=98% Package:0.1ml
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Xi'an Pure&True New Materials Co., Ltd.
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Product Name:(E)-1-(furan-3-yl)-4-methylpent-2-en-1-one
CAS:34348-59-9
Purity:>98.0% Package:1KG;5KG;10KG;100KG
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| | ISOEGOMAKETONE Basic information |
| Product Name: | ISOEGOMAKETONE | | Synonyms: | ISOEGOMAKETONE;(E)-1-(furan-3-yl)-4-methylpent-2-en-1-one;2-Penten-1-one, 1-(3-furanyl)-4-methyl-, (2E)-;(2E)-1-(3-Furyl)-4-methyl-2-penten-1-one;(2E)-1-(Furan-3-yl)-4-methylpent-2-en-1-one;(E)-1-(Furan-3-yl)-4-methylpent-2-en-1-one - [F90363] | | CAS: | 34348-59-9 | | MF: | C10H12O2 | | MW: | 164.2 | | EINECS: | | | Product Categories: | | | Mol File: | 34348-59-9.mol |  |
| | ISOEGOMAKETONE Chemical Properties |
| Boiling point | 70 °C(Press: 1 Torr) | | density | 1.002±0.06 g/cm3(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | ISOEGOMAKETONE Usage And Synthesis |
| Uses | Isoegomaketone is a sesquiterpenoid that can be isolated from Perilla frutescens essential oil. Isoegomaketone exhibits anti-inflammatory, antioxidant, anti-cancer, anti-mycobacterial, anti-arthritic and anti-obesity effects[1][2][3]. | | Definition | ChEBI: Isoegomaketone is an aromatic ketone. | | Synthesis Reference(s) | Synthesis, p. 991, 1984 DOI: 10.1055/s-1984-31051 | | Anticancer Research | This compound tested in in vivo models of B16 melanoma gave a significant cellgrowth inhibition. The tumor cells show an ROS-mediated mitochondria-dependentapoptotic-type death in sub-G1 cell cycle. Iso-egomaketone seemed to generateROS in cells as well as upregulation of Bax and Bcl-2expression (Russo et al. 2015;Shen et al. 2012). | | References | [1] Baer K H C, et al., Composition of the essential oil of Perilla frutescens (L.) Britton from Turkey[J]. Flavour and fragrance journal, 2003, 18(2): 122-123.
[2] Kim HM, et al., 9Hydroxyisoegomaketone inhibits LPSinduced NO and inflammatory cytokine production in RAW264.7 cells. Mol Med Rep. 2021 Mar;23(3):181. DOI:10.3892/mmr.2020.11820
[3] Kim HW, et al., Isoegomaketone exhibits potential as a new Mycobacterium abscessus inhibitor. Front Microbiol. 2024 Feb 23;15:1344914. DOI:10.3389/fmicb.2024.1344914 |
| | ISOEGOMAKETONE Preparation Products And Raw materials |
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