奎諾二甲基丙烯酸酯
| 中文名稱 | 奎諾二甲基丙烯酸酯 |
|---|---|
| 中文同義詞 | 奎諾二甲基丙烯酸酯;奎諾二甲基丙烯酸;水溶性維生素E/奎諾二甲基丙烯酸酯;奎諾二甲基丙烯酸酯(TROLOX);6-羥基-2,5,7,8-四甲基苯并二氫吡喃-2-羧酸;6-羥基-2,5,7,8-四甲基色滿-2-羧酸(97%);(±)-6-羥基-2,5,7,8-四甲基色滿-2-羧酸;(±)-6-羥基-2,5,7,8-四甲基色烷-2-羧酸 |
| 英文名稱 | Trolox |
| 英文同義詞 | 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2h-1-benzopyran-2-carboxylicaci;troloxc;6-HYDROXY-2,5,7,8-TETRAMETHYLCHROMAN-2-CARBOXYLIC ACID;TROLOX(R);TROLOXTM C;TIMTEC-BB SBB005933;trolox tm;(+/-)-6-HYDROXY-2,5,7,8-TETRAMETHYL-CHRO M.-2-CARBOXYL.AC |
| CAS號 | 53188-07-1 |
| 分子式 | C14H18O4 |
| 分子量 | 250.29 |
| EINECS號 | 258-422-8 |
| 相關類別 | 合成;小分子抑制劑;有機化合物;有機化工原料;體外診斷試劑;診斷試劑系列-診斷試劑系列;化學原料;化工產品-有機化工;化工原料 |
| Mol文件 | 53188-07-1.mol |
| 結構式 |  |
奎諾二甲基丙烯酸酯 性質
| 熔點 | 187-189 °C (lit.) |
|---|---|
| 沸點 | 313.42°C (rough estimate) |
| 密度 | 1.0616 (rough estimate) |
| 折射率 | 1.4970 (estimate) |
| 儲存條件 | 2-8°C |
| 溶解度 | 可溶于DMSO（高達25mg/ml）或乙醇（高達25mg/ml）。在堿性pH值下也可溶于水。 |
| 形態(tài) | 結晶粉末 |
| 酸度系數(shù)(pKa) | 3.35±0.20(Predicted) |
| 顏色 | 白色至淡米色 |
| 水溶解性 | water: 0.5mg/mL (slightly soluble) ethanol: 150mg/mL methanol: soluble |
| BRN | 1384051 |
| 穩(wěn)定性 | 可在-20°下的DMSO或乙醇溶液保存長達1個月。 |
| 化妝品成分功效 | 皮膚調理 |
| InChI | InChI=1S/C14H18O4/c1-7-8(2)12-10(9(3)11(7)15)5-6-14(4,18-12)13(16)17/h15H,5-6H2,1-4H3,(H,16,17) |
| InChIKey | GLEVLJDDWXEYCO-UHFFFAOYSA-N |
| SMILES | C1(C)(C(O)=O)OC2=C(C)C(C)=C(O)C(C)=C2CC1 |
| CAS 數(shù)據庫 | 53188-07-1(CAS DataBase Reference) |
| EPA化學物質信息 | 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid (53188-07-1) |
Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion.
Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or posttreatment of cells with Trolox reduced H
2
O
2
-induced DNA fragmentation to control levels and below. .
Trolox is a hydrophilic analogue of alpha-tocopherol and reported to scavenge peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. Trolox prolongs substantially the survival of human ventricular myocytes and hepatocyte against oxyradicals generated with xanthine oxidase plus hypoxanthine, and prevented lysis of red cells exposed to an azo-initiator.
一種來源于水溶性維生素e的抗氧化劑,具有自由基清除和抗氧化活性。
安全信息
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| 更新日期 | 產品編號 | 產品名稱 | CAS號 | 包裝 | 價格 |
|---|---|---|---|---|---|
| 2026/07/06 | 21894 | 6-羥基-2，5，7，8-四甲基色滿-2-羧酸(97%) Trolox™, 97%, Thermo Scientific Chemicals | 53188-07-1 | 25g | 6654元 |
| 2026/07/06 | S3665 | 奎諾二甲基丙烯酸酯 Trolox | 53188-07-1 | 100mg | 647.98元 |