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| | Simvastatin ammonium salt Basic information |
| Product Name: | Simvastatin ammonium salt | | Synonyms: | SIMVASTATIN AMMONIUM SALT;SIMVASTATIN HYDROXY ACID, AMMONIUM SALT;1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a;1-Naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-,d-dihydroxy-2,6-dimethyl-, monoammonium salt, (R,dR,1S,2S,6R,8S,8aR)- (9CI);Simvastatin impurity A;(3R,5R)-7-((1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoate ammonium salt;Simvastatin acid ammonium salt;(βR,δR,1S,2S,6R,8S,8aR)- | | CAS: | 139893-43-9 | | MF: | C25H43NO6 | | MW: | 453.62 | | EINECS: | 404-520-2;604-165-5 | | Product Categories: | Chiral Reagents;Heterocycles;Inhibitors;Intermediates & Fine Chemicals;HMG-CoA reductase;Metabolites & Impurities;Metabolites;Pharmaceuticals | | Mol File: | 139893-43-9.mol |  |
| | Simvastatin ammonium salt Chemical Properties |
| Melting point | 128-131°C | | vapor pressure | 0.001Pa at 25℃ | | storage temp. | -20°C | | solubility | DMSO (Sparingly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Off-White | | Water Solubility | 3.3g/L at 20℃ | | BRN | 4836426 | | Major Application | forensics and toxicology
pharmaceutical (small molecule) | | InChIKey | FFPDWNBTEIXJJF-OKDJMAGBSA-N | | LogP | 0.28 at 25℃ |
| Hazard Codes | Xi,T | | Risk Statements | 36/37/38-64-52/53-40-61 | | Safety Statements | 26-36-36/37/39-24/25-22-53 | | WGK Germany | 3 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Aquatic Chronic 3
Carc. 2
Repr. 1A |
| | Simvastatin ammonium salt Usage And Synthesis |
| Chemical Properties | White Powder | | Uses | A competitive inhibitor of HMG-CoA reductase. A metabolite of Simvastin | | Uses | A metabolite of Simvastin (S485000). A competitive inhibitor of HMG-CoA reductase. |
| | Simvastatin ammonium salt Preparation Products And Raw materials |
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