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| | 6,8-Diprenylorobol Basic information |
| Product Name: | 6,8-Diprenylorobol | | Synonyms: | 6,8-Diprenylorobol;4H-1-Benzopyran-4-one, 3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-;8-Diprenylorobol;5,7,3',4'-Tetrahydroxy-6,8-diprenylisoflavone | | CAS: | 66777-70-6 | | MF: | C25H26O6 | | MW: | 422.47 | | EINECS: | | | Product Categories: | | | Mol File: | 66777-70-6.mol |  |
| | 6,8-Diprenylorobol Chemical Properties |
| Boiling point | 667.1±55.0 °C(Predicted) | | density | 1.301±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | powder | | pka | 7.00±0.20(Predicted) | | color | Yellow |
| | 6,8-Diprenylorobol Usage And Synthesis |
| Uses | 6,8-Diprenylorobol, a prenylated isoflavone, is a nature product that could be isolated from the leaves of Cudrania tricuspidata. 6,8-Diprenylorobol antiproliferative effect and induces apoptosis through activation of p53 and generation of ROS[1][2]. | | target | Estrogen receptor | Antifection | HIV | Progestogen receptor | | References | [1] Choi YJ, et, al. 6,8-Diprenylorobol induces apoptosis in human colon cancer cells via activation of intracellular reactive oxygen species and p53. Environ Toxicol. 2021 May;36(5):914-925. DOI:10.1002/tox.23093
[2] Tuan Anh HL, et, al. Prenylated isoflavones from Cudrania tricuspidata inhibit NO production in RAW 264.7 macrophages and suppress HL-60 cells proliferation. J Asian Nat Prod Res. 2017 May;19(5):510-518. DOI:10.1080/10286020.2016.1232253 |
| | 6,8-Diprenylorobol Preparation Products And Raw materials |
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