| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Bis(4-methyl-1-piperazinylthiocarbonyl) disulfide, 98% CAS:20231-01-0 Purity:98% Package:250MG
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| Company Name: |
Thermo Fisher Scientific
|
| Tel: |
800-810-5118 |
| Email: |
cnchemical@thermofisher.com |
| Products Intro: |
Product Name:Bis(4-Methyl-1-piperazinylthiocarbonyl) disulfide, 98% CAS:20231-01-0 Purity:98% Package:250MG
|
BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE manufacturers
- EWP 815
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- $41.00
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2026-07-27
- CAS:20231-01-0
- Purity: 99.74%
- Supply Ability: 10g
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| | BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE Basic information |
| Product Name: | BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE | | Synonyms: | 4-methylpiperazino-thiuramdisulfide;disulfide,bis((4-methyl-1-piperazinyl)thiocarbonyl);BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE;EWP 815;4-METHYLPIPERAZINO-THIURAMDISULPHIDE;Bis(4-methyl-1-piperazinylthiocarbonyl) disulfide,98%;4-Methylpiperazine-1-carbothioic dithioperoxyanhydride;Piperazine, 1,1'-(dithiodicarbonothioyl)bis[4-methyl- | | CAS: | 20231-01-0 | | MF: | C12H22N4S4 | | MW: | 350.59 | | EINECS: | 247-450-6 | | Product Categories: | | | Mol File: | 20231-01-0.mol |  |
| | BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE Chemical Properties |
| Melting point | 142-143 °C | | Boiling point | 450.5±55.0 °C(Predicted) | | density | 1.339±0.06 g/cm3(Predicted) | | pka | 6.63±0.42(Predicted) | | form | Solid | | color | White to off-white | | InChI | 1S/C12H22N4S4/c1-13-3-7-15(8-4-13)11(17)19-20-12(18)16-9-5-14(2)6-10-16/h3-10H2,1-2H3 | | InChIKey | OOBDBFPYJXJEHC-UHFFFAOYSA-N | | SMILES | CN1CCN(C(SSC(N2CCN(C)CC2)=S)=S)CC1 |
| Safety Statements | 24/25 | | WGK Germany | WGK 3 | | HS Code | 29335995 | | Storage Class | 11 - Combustible Solids | | Toxicity | LD50 oral in rat: > 5gm/kg |
| Provider | Language |
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ACROS
| English |
| | BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE Usage And Synthesis |
| Chemical Properties | yellow crystalline powder | | Uses | EWP 815 is a disulfiram analogue, is a potent inhibitor of Ins(1,4)P2 phosphatase and Ins(1,4,5)P3 5-phosphatase. EWP 815 also inhibits enzyme dopamine β-hydroxylase activity[1][2]. | | in vivo | EWP 815 (50 mg/kg; i.p.; 30 min before killed) inhibits the enzyme dopamine β-hydroxylase activity in mice[2].
| Animal Model: | Female mice (20 g)[2] | | Dosage: | 50 mg/kg | | Administration: | Intraperitoneal injection; 30 min before killed | | Result: | Intraperitoneal injection; 30 min before killedInhibited β-hydroxylase of 3H-α-methyldopamine.
Reduced the amount of 3H-α-Me-NA by 12%. |
| | References | [1] Fowler CJ, et al. Inhibition of inositol 1,4,5-trisphosphate 5-phosphatase by micromolar concentrations of disulfiram and its analogues. Biochem J. 1993 Feb 1;289 ( Pt 3)(Pt 3):853-9. DOI:10.1042/bj2890853 [2] Carlsson A, et al. On the beta-hydroxylation of (+-)-alpha-methyldopamine in vivo. Eur J Pharmacol. 1968 Dec;5(1):85-92. DOI:10.1016/0014-2999(68)90160-x |
| | BIS(4-METHYL-1-PIPERAZINYLTHIOCARBONYL) DISULFIDE Preparation Products And Raw materials |
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