| Company Name: |
BioBioPha Co., Ltd.
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| Tel: |
0871-65217109 |
| Email: |
y.liu@mail.biobiopha.com |
| Products Intro: |
Product Name:Bakkenolide B
CAS:18455-98-6
Purity:97.5% Package:5mg Remarks:BBP04203
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| Company Name: |
Shanghai Tauto Biotech Co., Ltd.
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| Tel: |
021-51320588 |
| Email: |
tauto@tautobiotech.com |
| Products Intro: |
Product Name:Bakkenolide B; Fukinolide
CAS:18455-98-6
Purity:more than 98% HPLC Package:10mg;20mg;1g;10g;100g standard packing or according to customers' requirement
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| | Fukinolide Basic information |
| Product Name: | Fukinolide | | Synonyms: | Fukinolide;(-)-Bakkenolide B;(1'R,3R,7'aβ)-1'β-Acetoxy-3'aβ,4'β-dimethyl-4-methylene-7'α-[[(2Z)-2-methyl-2-butenoyl]oxy]spiro[oxolane-3,2'-hydrindane]-2-one;(Z)-2-Methyl-2-butenoic acid [(3R,3'aα)-3'α-acetoxy-4,5,1',3',3'a,4',5',6',7',7'a-decahydro-7'α,7'aα-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'β-yl] ester;Bakkenolide B;2-Butenoic acid, 2-methyl-, (2'R,3'R,3'aR,4'S,7'S,7'aR)-3'-(acetyloxy)decahydro-7',7'a-dimethyl-4-methylene-2-oxospiro[furan-3(2H),2'-[2H]inden]-4'-yl ester, (2Z)-;Spironolactone EP Impurity 16 | | CAS: | 18455-98-6 | | MF: | C22H30O6 | | MW: | 390.47 | | EINECS: | | | Product Categories: | | | Mol File: | 18455-98-6.mol |  |
| | Fukinolide Chemical Properties |
| Melting point | 101-102 °C | | Boiling point | 503.0±50.0 °C(Predicted) | | density | 1.16±0.1 g/cm3(Predicted) |
| | Fukinolide Usage And Synthesis |
| Uses | Bakkenolide B is isolated from petasites japonicas leaves and hasanti-allergic and anti-inflammatory effects. Bakkenolide B can be used for the study of asthma[1]. | | Definition | ChEBI: Bakkenolide B is a terpene lactone. | | in vivo | Bakkenolide B (intraperitoneal injection; 1 mg/ml; 1 h before ovalbumin nebulization on days 28, 29, and 30) strongly inhibits the accumulation of eosinophils, macrophages, and lymphocytes to bronchoalveolar lavage fluid (BALF) in ovalbumin-induced asthma mice[1]. | Animal Model: | Ovalbumin-induced asthma mice[1] | | Dosage: | 1 mg/ml | | Administration: | Intraperitoneal injection; 1 h before ovalbumin nebulization on days 28, 29, and 30 | | Result: | Exhibited anti-allergic effects in mice. |
| | References | [1] Lee KP, et al. Anti-allergic and anti-inflammatory effects of bakkenolide B isolated from Petasites japonicus leaves.J Ethnopharmacol.2013 Jul 30;148(3):890-4. DOI:10.1016/j.jep.2013.05.037 |
| | Fukinolide Preparation Products And Raw materials |
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