HIV-RT inhibitor 1 manufacturers
- GSK2838232
-
- $54.00
-
2026-07-27
- CAS:1443460-91-0
- Purity: 99.05%
- Supply Ability: 10g
|
| | HIV-RT inhibitor 1 Basic information |
| Product Name: | HIV-RT inhibitor 1 | | Synonyms: | HIV-RT inhibitor 1;28-Norlup-18-en-21-one, 3-(3-carboxy-3-methyl-1-oxobutoxy)-17-[(1R)-2-[[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino]-1-hydroxyethyl]-, (3β)-;GSK 2838232,GSK-2838232,Human immunodeficiency virus,GSK2838232,Inhibitor,HIV,inhibit;4-{[(3aR,5aR,5bR,7aR,9S,11aR,11bR,13aS)-3a-[(1R)-2-{[(4-chlorophenyl)methyl][2-(dimethylamino)ethyl]amino}-1-hydroxyethyl]-5a,5b,8,8,11a-pentamethyl-2-oxo-1-(propan-2-yl)-2H,3H,3aH,4H,5H,5aH,5bH,6H,7H,7aH,8H,9H,10H,11H,11aH,11bH,12H,13H,13aH-cyclopenta[a]chrysen-9-yl]oxy}-2,2-dimethyl-4-oxobutanoic acid;GSK2838232, 10 mM in DMSO;4-(((3ar,5ar,5br,9s,11ar,11br,13as)-3a-((r)-2-((4-chlorobenzyl)(2-(dimethylamino)ethyl)amino)-1-hydroxyethyl)-1-isopropyl-5a,5b,8,8,11a-pentamethyl-2-oxo-3,3a,4,5,5a,5b,6,7,7a,8,9,10,11,11a,11b,12,13,13a-octadecahydro-2h-cyclopenta[a]chrysen-9-yl)oxy)-2,2-dimethyl-4-oxobutanoic acid | | CAS: | 1443460-91-0 | | MF: | C48H73ClN2O6 | | MW: | 809.57 | | EINECS: | | | Product Categories: | | | Mol File: | 1443460-91-0.mol |  |
| | HIV-RT inhibitor 1 Chemical Properties |
| Boiling point | 817.1±65.0 °C(Predicted) | | density | 1.17±0.1 g/cm3(Predicted) | | storage temp. | Store at 0-8 °C | | solubility | DMSO:25.0(Max Conc. mg/mL);30.88(Max Conc. mM) | | form | A crystalline solid | | pka | 4.48±0.28(Predicted) | | color | White to off-white |
| | HIV-RT inhibitor 1 Usage And Synthesis |
| Description | GSK2838232 is a second generation inhibitor of HIV-1 maturation (IC90 = 6.4 nM). It is active against a variety of HIV isolates resistant to bevirimat (PA-457; ). | | Uses | GSK2838232 inhibit HIV reverse transcriptase activity across a broad panel of HIV-1 isolates, extracted from patent WO/2013090664A1, compound51. | | References | [1] Hatcher Mark Andrew, et al. Preparation of betulin derivatives for the treatment of HIV. From PCT Int. Appl. (2013), WO 2013090664 A1 20130620. |
| | HIV-RT inhibitor 1 Preparation Products And Raw materials |
|