| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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18930552037 |
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3bsc@sina.com |
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Product Name:DEA;N-(2-Hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenaMide
CAS:150314-35-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
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info@emmx.com |
| Products Intro: |
Product Name:DEA
CAS:150314-35-5
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| Product Name: | DEA | | Synonyms: | 7,10,13,16-docosatetraenylethanolamide;7,10,13,16-Docosatetraenamide, N-(2-hydroxyethyl)-, (all-Z)-;7,10,13,16-Dtea;N-(2-HYDROXYETHYL)-7Z, 10Z, 13Z, 16Z-DOCOSATETRAENAMIDE;N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide (all-Z)-;7,10,13,16-Docosatetraenoylethanolamine;Anandamide (22:4, n-6) (Docosatetraenylethanolamide);(7Z,10Z,13Z,16Z)-N-(2-hydroxyethyl)docosa-7,10,13,16-tetraenamide | | CAS: | 150314-35-5 | | MF: | C24H41NO2 | | MW: | 375.59 | | EINECS: | | | Product Categories: | Cannabinoid receptor | | Mol File: | 150314-35-5.mol |  |
| Boiling point | 544.5±50.0 °C(Predicted) | | density | 0.932±0.06 g/cm3(Predicted) | | storage temp. | Desiccate at -20°C | | solubility | DMF: 10 mg/ml; DMSO: 30 mg/ml; Ethanol: 100 mg/ml; Ethanol:PBS (1:2): 8 mg/ml; PBS (pH 7.2): <100 μg/ml | | pka | 14.49±0.10(Predicted) |
| Description | Docosatetraenoyl ethanolamide (DEA) is an endocannabinoid containing docosatetraenoic acid in place of the arachidonate moiety of AEA. DEA acts on CB1 receptors with potency and efficacy similar to that of AEA. However, its specific role and relative importance as a cannabinergic neurotransmitter have not been elucidated. | | Uses | (7Z,10Z,13Z,16Z)-N-(2-Hydroxyethyl)-7,10,13,16-docosatetraenamide is an endocannabinoid and an analog of anandamide, which is an endogenous cannabinoid and TRPV1 receptor agonist. | | Definition | ChEBI: 7,10,13,16-Docosatetraenoylethanolamine is a N-acylethanolamine 22:4. | | Biological Activity | Potent endocannabinoid ( anandamide analog) that activates CB 1 receptors in microglia and binds to rat synaptosomal membranes (K I = 34.4 nM). Cannabimimetic in vivo . | | IC 50 | CB1 | | References | [1] LUMIR HANUS. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor[J]. Journal of Medicinal Chemistry, 1993, 36 20: 3032-3034. DOI: 10.1021/jm00072a026 |
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