| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:(E)-Guanabenz
CAS:60329-03-5
Package:50mg/RMB 19420;100mg/RMB 24625;25mg/RMB 14900
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2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine manufacturers
- (E)-Guanabenz
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- $2785.00
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2026-05-11
- CAS:60329-03-5
- Purity:
- Supply Ability: 10g
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| | 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine Basic information |
| | 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine Chemical Properties |
| | 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine Usage And Synthesis |
| Uses | (E)-Guanabenz ((E)-Wy-8678) is an orally active central α2-adrenoceptor agonist. (E)-Guanabenz has antihypertensive activity, acts via stimulating central α2-adrenoceptors, and reducing net sympathetic outflow into the periphery. (E)-Guanabenz also directly binds to and inhibits GADD34, and has neuroprotective activity. (E)-Guanabenz can be used for researching hypertension and Parkinson disease[1][2]. | | Definition | ChEBI: Guanabenz is a dichlorobenzene. | | IC 50 | α adrenergic receptor | | References | [1] Sun X, et al. Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease. Exp Neurol. 2018 May;303:95-107. DOI:10.1016/j.expneurol.2018.01.015
[2] Xie J, et al. LC-MS/MS determination of guanabenz E/Z isomers and its application to in vitro and in vivo DMPK profiling studies. J Pharm Biomed Anal. 2021 Oct 25;205:114331. DOI:10.1016/j.jpba.2021.114331 |
| | 2-[(E)-(2,6-dichlorophenyl)methylideneamino]guanidine Preparation Products And Raw materials |
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