ChemicalBook > Product Catalog >Pharmaceutical intermediates >Heterocyclic compound >BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Suppliers list
Company Name: Hinova Pharma
Tel: +86-18190684138 +86-18190684138
Email: xhchen00241@hinovapharma.com
Products Intro: Product Name:7H-benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
CAS:23749-58-8
Purity:0.97 Package:5KG;1KG;500g;100g;10g;
Company Name: CONIER CHEM AND PHARMA LIMITED
Tel: +8618523575427
Email: sales@conier.com
Products Intro: Product Name:7h-benzimidazo(2,1-a)benzo(de)isoquinolin-7-one
CAS:23749-58-8
Purity:0.99 Package:1kg
Company Name: Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd
Tel: +86-86-22-87899925 +86-8618522618860
Email: 18522618860@163.com
Products Intro: Product Name:BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
CAS:23749-58-8
Purity:0.99 Package:Various Packaging; segregation
Company Name: Zhengzhou Alfa Chemical Co.,Ltd
Tel: +8618530059196
Email: sale04@alfachem.cn
Products Intro: CAS:23749-58-8
Purity:95% Min. Package:100g; 500g; 1kg; 25kg;bulk package
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:7H-Benzimidazo(2,1-a)benz(de)isoquinolin-7-one
CAS:23749-58-8
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE manufacturers

  • Solvent Yellow 184
  • Solvent Yellow 184 pictures
  • $10.00
  • 2021-10-19
  • CAS:23749-58-8
  • Min. Order: 1Kg/Bag
  • Purity: 99%
  • Supply Ability: 20 Tons
  • Solvent Yellow 184
  • Solvent Yellow 184 pictures
  • $10.00
  • 2021-10-11
  • CAS:23749-58-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 20 tons
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Basic information
Product Name:BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
Synonyms:7h-benzimidazo(2,1-a)benz(de)isoquinolin-7-one;luminoforyellow-green490rt;luminogren;7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one 98%;7H-Benzimidazo[2,1-a]benzo[de]isoquinolin-7-one;BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE;7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one98%;luminophor2
CAS:23749-58-8
MF:C18H10N2O
MW:270.28
EINECS:245-865-7
Product Categories:
Mol File:23749-58-8.mol
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Structure
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Chemical Properties
Melting point 189 °C
Boiling point 613.6±38.0 °C(Predicted)
density 1.40±0.1 g/cm3(Predicted)
pka2.05±0.20(Predicted)
form powder
color Bright yellow
InChIInChI=1S/C18H10N2O/c21-18-13-8-4-6-11-5-3-7-12(16(11)13)17-19-14-9-1-2-10-15(14)20(17)18/h1-10H
InChIKeyNZBSAAMEZYOGBA-UHFFFAOYSA-N
SMILESC12=NC3=CC=CC=C3N1C(=O)C1=CC=CC3=CC=CC2=C13
Safety Information
HS Code 2933998090
MSDS Information
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Usage And Synthesis
UsesAHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].
ApplicationBENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE is a derivative of  benzimidazo[2,1-a]benz[d,e]isoquinolion-7-one fluorophore, which is known to enter the cells and localize into the acidic organelles[2].
Properties and Applications

TEST ITEMS

SPECIFICATION

APPEARANCE

YELLOW POWDER

SHADE

GREENISH

HEAT RESISTANCE

260 °C min

LIGHT FASTNESS

5-6

ACID RESISTANCE

5

ALKALI RESISTANCE

5

WATER RESISTANCE

5

DENSITY

1.20 g/cm 3

RESIDUE ON 80 MESH

5.0% max

WATER SOLUBLE

1.0% max

VOLATITE 105 °C

1.0% max

TINTING STRENGTH

100-105 %

WEIGHT METAL TOTAL

50ppm max

References [1] Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. DOI:10.1021/acsptsci.2c00253
[2] Faggi, E., Luis, S. V., & Alfonso, I. (2019). Sensing, Transport and Other Potential Biomedical Applications of Pseudopeptides. Current Medicinal Chemistry, 26 21<, 4065–4097. https://doi.org/10.2174/0929867325666180301091040
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE Preparation Products And Raw materials
Tag:BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE(23749-58-8) Related Product Information
COUMARIN 7 4-[(2,4-Dimethylphenyl)azo]-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-one Solvent Yellow 179 Solvent Yellow 183 1H-Benz[de]isoquinoline-1,3(2H)-dione,2-(2-hydroxyethyl)-6-(4-morpholinyl)- Solvent Yellow 177 SOLVENT YELLOW 182 Solvent Yellow 186 Solvent Yellow 178 Vat Red 15 Vat Red 14 Vat Orange 7 BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE 7-OXO-7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOLINE-3-CARBOXYLIC ACID ACETATE Disalicylalazine (Luminore yellow 540 T) anthra[1,2-c]benzimidazo[2,1-i]benzo[lmn][2,8]phenanthroline-5,9,20(6H)-trione 4-[5-(4-METHOXYPHENYL)-1-(2-NAPHTHYL)-4,5-DIHYDRO-1H-PYRAZOLE-3-YL]-7H-BENZIMIDAZO[2,1-A]BENZO[DE]ISOQUINOLIN-7-ONE Bisbenzimidazo2,1-a:1',2'-b'anthra2,1,9-def:6,5,10-d'e'f'diisoquinoline-6,11-dione(mixturewithcis-isomer)