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| | Acefylline piperazinate Basic information |
| Product Name: | Acefylline piperazinate | | Synonyms: | 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7h-purine-7-aceticacicompd.wit;1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7h-purine-7-aceticacidcompd.with;acefyllinepiperazinesalt;acefyllinpiperazinate;aethaphyllinium;dynaphylline;piperazinetheophyllineethanoate;theophyllineethanoateofpiperazine | | CAS: | 18833-13-1 | | MF: | C13H20N6O4 | | MW: | 324.34 | | EINECS: | 242-614-3 | | Product Categories: | | | Mol File: | 18833-13-1.mol |  |
| | Acefylline piperazinate Chemical Properties |
| | Acefylline piperazinate Usage And Synthesis |
| Uses | Acefylline piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research[1][2][3]. | | References | [1] Ferretti C, et al. Inhibitory effect of theophylline, theophylline-7-acetic acid, ambroxol and ambroxol-theophylline-7-acetate on rat lung cAMP phosphodiesterase isoenzymes. Int J Tissue React. 1992;14(1):31-6. PMID:1328102
[2] Méchin MC, et, al. Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis. J Dermatol Sci. 2016 Feb;81(2):101-6. DOI:10.1016/j.jdermsci.2015.11.006
[3] Tsvetkova B, Tencheva J, Peikov P. Esterification of 7-theophyllineacetic acid with diethylene glycol monomethyl ether. Acta Pharm. 2006 Jun;56(2):251-7. PMID: 16613730. PMID:16613730 |
| | Acefylline piperazinate Preparation Products And Raw materials |
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