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| | Cuscohygrine Basic information |
| Product Name: | Cuscohygrine | | Synonyms: | 1,3-bis[(2s)-1-methylpyrrolidin-2-yl]propan-2-one;cuscohygrine;1,3-bis(1-methyl-2-pyrrolidinyl)acetone;1,3-BIS(1-METHYL-2-PYRROLIDINYL)PROPANONE;Cuskhygrine;Hellaradine;1,3-Bis[1-methylpyrrolidin-2-yl]propan-2-one;C06521 | | CAS: | 454-14-8 | | MF: | C13H24N2O | | MW: | 224.34 | | EINECS: | | | Product Categories: | Heterocycles | | Mol File: | 454-14-8.mol |  |
| | Cuscohygrine Chemical Properties |
| Melting point | （152（14 mmHg）） | | Boiling point | bp23 169-170°; bp14 152°; bp2 118-125° | | density | d420 0.9733 | | refractive index | nD20 1.4832 | | storage temp. | -20°C Freezer | | solubility | Chloroform (Soluble), Ethyl Acetate, Methanol (Slightly) | | form | Oil | | color | Clear Colourless to Light Yellow | | Stability: | Solutions are unstable. |
| | Cuscohygrine Usage And Synthesis |
| Chemical Properties | Clear Colourless Oil | | Uses | It was the main alkaloid found in medicinal plants Datura metel. | | Definition | ChEBI: Cuscohygrine is a N-alkylpyrrolidine and a pyrrolidine alkaloid. | | Synthesis | When 1-methyl-2-tetrahydropyrrolidone was used as the raw material for the synthesis of red crotonine, a small amount of unreacted raw material existed due to the control of reaction conditions during the synthesis process, which affected the product quality. In order to separate them, we found the appropriate thin-layer chromatographic conditions after several tests, and the separation of the chromatographic spots obtained more satisfactory results.
Atropine workshop to extract tropine alkaloids left mother liquor, separation of hydrobromide to obtain the red crocodiline, the latter's aqueous solution by ammonia, chloroform extraction, drying, remove chloroform, distillation under pressure, that is, to obtain the red crocodiline: boiling point, 178 a 179. |
| | Cuscohygrine Preparation Products And Raw materials |
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