| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:DENV-IN-4 CAS:2762302-75-8 Package:100mg/RMB 24625;25mg/RMB 14900;50mg/RMB 19420
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1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- manufacturers
- DENV-IN-4
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- $3520.00
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2026-04-21
- CAS:2762302-75-8
- Purity:
- Supply Ability: 10g
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| | 1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- Basic information |
| Product Name: | 1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- | | Synonyms: | DENV-IN-4;1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- | | CAS: | 2762302-75-8 | | MF: | C28H32N4O4Si | | MW: | 516.66 | | EINECS: | | | Product Categories: | | | Mol File: | 2762302-75-8.mol | ![1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- Structure](CAS/20211123/GIF/2762302-75-8.gif) |
| | 1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- Chemical Properties |
| Boiling point | 615.5±65.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | pka | 1.47±0.40(Predicted) |
| | 1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- Usage And Synthesis |
| Uses | DENV-IN-4 is a potent DENV inhibitor (DENV EC50=4.79 μM, Vero CC50>100 μM, SI>20.9). DENV-IN-4 can inhibit the expression level of DENV2 with concentration-dependence and reduce RNA-dependent RNA polymerase (RdRp) enzymatic activity. DENV-IN-4 has antiviral effect[1]. | | References | [1] Qian W, et al. Design, synthesis, discovery and SAR of the fused tricyclic derivatives of indoline and imidazolidinone against DENV replication and infection [published online ahead of print, 2022 Jan 24]. Bioorg Chem. 2022;120:105639. DOI:10.1016/j.bioorg.2022.105639 |
| | 1H-Imidazo[1,5-a]indol-1-one, 3-[4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]phenyl]-2,3,9,9a-tetrahydro-2-[(4-nitrophenyl)amino]-, (3R,9aS)- Preparation Products And Raw materials |
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