| Company Name: |
Varanous Labs Pvt Ltd
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| Tel: |
+91-7036248882 |
| Email: |
bheemashankar.e@varanouslabs.com |
| Products Intro: |
Product Name:Abacavir amine impurity
CAS:124752-25-6
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
SynThink RESEARCH CHEMICALS
|
| Tel: |
+91-8177860948 |
| Email: |
bd@synthinkchemicals.com |
| Products Intro: |
Product Name:Abacavir EP Impurity C
CAS:124752-25-6
Purity:98% Package:25mg, 50mg,100mg,200mg
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| | 6-aminocarbovir Basic information |
| Product Name: | 6-aminocarbovir | | Synonyms: | Abacavir Related CoMpound A;6-aminocarbovir;(-)-2,6-Diamino-9-[(1R)-4β-(hydroxymethyl)-2-cyclopentene-1β-yl]-6,9-dihydro-1H-purine;2-Cyclopentene-1-methanol, 4-(2,6-diamino-9H-purin-9-yl)-, (1S-cis)-;Descyclopropyl Abacavir;Abacavir Related Compound A (20 mg) ([4-(2,6-diamino-9H-purin-9-yl)cyclopent-2-enyl]methanol);(1S,4R)-4-(2,6-DiaMino-9H-purin-9-yl)-2-cyclopentene-1-Methanol;(1α,4α)-4-(2,6-Diamino-9H-purin-9-yl)-2-cyclopentenyl-carbinol | | CAS: | 124752-25-6 | | MF: | C11H14N6O | | MW: | 246.27 | | EINECS: | | | Product Categories: | Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals | | Mol File: | 124752-25-6.mol |  |
| | 6-aminocarbovir Chemical Properties |
| Melting point | 180-182°C | | Boiling point | 628.2±65.0 °C(Predicted) | | density | 1.75±0.1 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 14.86±0.10(Predicted) | | color | Off-White to Pale Yellow | | Major Application | pharmaceutical | | InChI | 1S/C11H14N6O/c12-9-8-10(16-11(13)15-9)17(5-14-8)7-2-1-6(3-7)4-18/h1-2,5-7,18H,3-4H2,(H4,12,13,15,16)/t6-,7+/m1/s1 | | InChIKey | ZKJUXHDSLJYKED-RQJHMYQMSA-N | | SMILES | [n]2(c3nc(nc(c3nc2)N)N)[C@@H]1C[C@@H](C=C1)CO |
| Hazard Codes | Xi | | Risk Statements | 41-43 | | Safety Statements | 26-36/37-39 | | WGK Germany | WGK 3 | | HS Code | 2933599550 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Dam. 1 |
| | 6-aminocarbovir Usage And Synthesis |
| Chemical Properties | Off-White to Pale Yellow Solid | | Uses | Abacavir Intermediate. | | Uses | Descyclopropyl Abacavir (Abacavir EP Impurity C; Abacavir Related Compound A) is an intermediate of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively. |
| | 6-aminocarbovir Preparation Products And Raw materials |
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