(2R,3R,4R)-2-羥甲基哌啶-3,4-二醇
| 中文名稱 | (2R,3R,4R)-2-羥甲基哌啶-3,4-二醇 |
|---|---|
| 中文同義詞 | 蕎麥堿;桑葉生物堿;(2R,3R,4R)-2-羥甲基哌啶-3,4-二醇;蕎麥堿, >98%;喬麥堿;FAGOMINE,蕎麥堿;法古米;蕎麥堿標(biāo)準(zhǔn)品 |
| 英文名稱 | fagomine |
| 英文同義詞 | fagomine;(2R)-2-(Hydroxymethyl)piperidine-3β,4α-diol;(2R)-2α-(Hydroxymethyl)piperidine-3β,4α-diol;(2R)-3β,4α-Dihydroxypiperidine-2α-methanol;1,2,5-Trideoxy-1,5-epimino-D-xylo-hexitol;(2R,3R,4R)-3,4-Dihydroxy-2-piperidinemethanol;(2R,3R,4R)-2-(Hydroxymethyl)piperidine-3,4-diol;3,4-Piperidinediol,2-(hydroxyMethyl)-, (2R,3R,4R)- |
| CAS號(hào) | 53185-12-9 |
| 分子式 | C6H13NO3 |
| 分子量 | 147.17 |
| EINECS號(hào) | |
| 相關(guān)類別 | 植物提取物;對照品;標(biāo)準(zhǔn)品 -中藥標(biāo)準(zhǔn)品 |
| Mol文件 | 53185-12-9.mol |
| 結(jié)構(gòu)式 |  |
(2R,3R,4R)-2-羥甲基哌啶-3,4-二醇 性質(zhì)
| 熔點(diǎn) | 185-186℃ |
|---|---|
| 沸點(diǎn) | 315.4±42.0 °C(Predicted) |
| 密度 | 1.279 |
| 形態(tài) | 固體 |
| 酸度系數(shù)(pKa) | 14.16±0.60(Predicted) |
| 顏色 | 白色至卡其色 |
| LogP | -0.880 (est) |
Glycosidase
Fagomine (D-fagomine) is an iminosugar that has been shown to selectively agglutinate Enterobacteriales in vitro. Fagomine selectively agglutinates fimbriated enterobacteria (e.g., E.coli ) and inhibits their adhesion to the intestinal mucosa; the reason for this is probably related to its structural similarity with lectin-binding saccharides (e.g., mannose). Fagomine is capable of altering this effect of high-fat high-sucrose diet (HFHS) on the proportion of Enterobacteriales and E.coli .
Fagomine (D-fagomine) is a natural iminosugar that counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales. Compare to the standard group, rats fed high-fat high-sucrose diet (HFHS) with Fagomine (D-fagomine) gain significantly less weight (15.3%) than those fed HFHS (20.9%).
安全信息
| 更新日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-13005 | (2R,3R,4R)-2-羥甲基哌啶-3,4-二醇 Fagomine | 53185-12-9 | 1 mg | 2045元 |
| 2026/06/05 | HY-13005 | (2R,3R,4R)-2-羥甲基哌啶-3,4-二醇 Fagomine | 53185-12-9 | 5mg | 4500元 |