| Company Name: |
PT CHEM GROUP LIMITED |
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+86-85511178; |
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peter68@ptchemgroup.com |
| Products Intro: |
Product Name:(6E,10Z,14Z)-6,14-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,12,13,15a-octahydrocyclotetradeca[b]furan-10-carboxylic acid
CAS:59632-76-7
Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:Wholesale price
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| Company Name: |
Nanjing Meihao Pharmaceutical Technology Co., Ltd.
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| Tel: |
meitaochem@126.com |
| Email: |
meitaochem@126.com |
| Products Intro: |
Product Name:(6E,10Z,14Z)-6,14-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,12,13,15a-octahydrocyclotetradeca[b]furan-10-carboxylic acid
CAS:59632-76-7
Purity:99% HPLC Package:1g;5g;10g;
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| | Anisomelic acid Basic information |
| Product Name: | Anisomelic acid | | Synonyms: | (3aR,6E,10Z,14E,15aS)-2,3,3a,4,5,8,9,12,13,15a-Decahydro-6,14-dimethyl-3-methylene-2-oxocyclotetradeca[b]furan-10-carboxylic acid;Anisomelic acid;Anisomelolide;Nsc272354;(6E,10Z,14Z)-6,14-dimethyl-3-methylidene-2-oxo-3a,4,5,8,9,12,13,15a-octahydrocyclotetradeca[b]furan-10-carboxylic acid;Cyclotetradeca[b]furan-10-carboxylic acid, 2,3,3a,4,5,8,9,12,13,15a-decahydro-6,14-dimethyl-3-methylene-2-oxo-, (3aR,6E,10Z,14E,15aS)- | | CAS: | 59632-76-7 | | MF: | C20H26O4 | | MW: | 330.42 | | EINECS: | | | Product Categories: | | | Mol File: | 59632-76-7.mol |  |
| | Anisomelic acid Chemical Properties |
| InChIKey | SORYERHBQFTRIK-PUWPUPSASA-N | | SMILES | O1C(=O)C(=C)[C@@]2([H])CCC(C)=CCCC(C(O)=O)=CCCC(C)=C[C@]12[H] |t:10,17,22| |
| | Anisomelic acid Usage And Synthesis |
| Description |
Anisomelic acid: a cembrane-type macrocyclic diterpenoid possesses both anticancer and antiviral activity
Anisomelic acid (AA) is one of the principle bioactive compounds isolated from the plant Anisomeles malabarica. It is a membrane-type macrocyclic diterpenoid that presents potent cytotoxicity. It possesses both anticancer and antiviral activity. Researchers have studied the mode of action of AA-mediated apoptosis, indicating that AA inhibits the expression of the E6 and E7 viral proteins. In addition, AA is also effective in inducing apoptosis in other HPV-positive cervical cancer cells, with a high degree of specificity to HPV-positive cells and insignificant effects on HPV-negative cells[1-2].
| | References |
[1] Rajendran Senthilkumar. “Synthesis and Evaluation of Anisomelic acid-like Compounds for the Treatment of HPV-Mediated Carcinomas.” Scientific Reports (2019): 20295.
[2] Christo Paul Preethy. “Analysis of the Cytotoxic Potential of Anisomelic Acid Isolated from Anisomeles malabarica.” Scientia Pharmaceutica 81 2 (2013): 559–66.
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| | Anisomelic acid Preparation Products And Raw materials |
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