(±)-Nebivolol-d4 (hydrochloride)
| 中文名稱 | (±)-Nebivolol-d4 (hydrochloride) |
|---|---|
| 中文同義詞 | (±)-奈必洛爾-d4(鹽酸鹽);(+)-N-乙基洛爾-d4 鹽酸鹽 |
| 英文名稱 | (+)-Nebivolol-d4 Hydrochloride |
| 英文同義詞 | (+)-Nebivolol-d4 Hydrochloride;(αS,α'S,2R,2'S)-α,α'-[IMinobis(Methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-Methanol]-d4 Hydrochloride;[2S-[2R*[R*[R*(S*)]]]]-α,α'-[IMinobis (Methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-Methanol-d4 Hydrochloride;(S,R,R,R)-Nebivolol-d4 Hydrochloride;(αR,α'R,2R,2'S)-α,α'-[IMinobis(Methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-Methanol]-d4;[2R-[2R*[R*[R*(S*)]]]]-α,α'-[IMinobis(Methylene)]bis[6-fluoro-3,4- dihydro-2H-1-benzopyran-2-Methanol-d4 Hydrochloride;Dexnebivolol-d4 Hydrochloride;d-Nebivolol-d4 Hydrochloride |
| CAS號(hào) | 2701283-32-9 |
| 分子式 | C22H26ClF2NO4 |
| 分子量 | 441.8959464 |
| EINECS號(hào) | |
| 相關(guān)類別 | Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals |
| Mol文件 | 2701283-32-9.mol |
| 結(jié)構(gòu)式 |  |
(±)-Nebivolol-d4 (hydrochloride) 性質(zhì)
| 熔點(diǎn) | 180-185°C |
|---|---|
| 儲(chǔ)存條件 | Hygroscopic, -20°C Freezer, Under Inert Atmosphere |
| 溶解度 | 可溶于二甲基亞砜、甲醇 |
| 形態(tài) | 固體 |
| 顏色 | 灰白色至淺棕褐色 |
(Rac)-Nebivolol-d4 hydrochloride 是 Nebivolol 氘代消旋體。Nebivolol 是β1-腎上腺素受體選擇性抑制劑，IC50 為 0.8 nM。