| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:CAY10575 CAS:916985-21-2 Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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CAY10575 manufacturers
- CAY10575
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- $95.00
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2026-05-11
- CAS:916985-21-2
- Purity:
- Supply Ability: 10g
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| | CAY10575 Basic information |
| Product Name: | CAY10575 | | Synonyms: | CAY10575;5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[4-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarboxamide;2-Thiophenecarboxamide, 5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[4-(methylsulfonyl)phenyl]methoxy]-;CAY10575, IKK-epsilon inhibitor | | CAS: | 916985-21-2 | | MF: | C22H21N3O6S2 | | MW: | 487.55 | | EINECS: | | | Product Categories: | | | Mol File: | 916985-21-2.mol |  |
| | CAY10575 Chemical Properties |
| Boiling point | 735.4±70.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 1mg/mL; DMSO: 10mg/mL; DMSO:PBS(7.2pH) 1:4: 0.2mg/mL | | form | A crystalline solid | | pka | 15.02±0.50(Predicted) | | color | tan | | InChI | 1S/C22H21N3O6S2/c1-29-17-8-15-16(9-18(17)30-2)25(12-24-15)20-10-19(21(32-20)22(23)26)31-11-13-4-6-14(7-5-13)33(3,27)28/h4-10,12H,11H2,1-3H3,(H2,23,26) | | InChIKey | YYZTVTZCYVZGRB-UHFFFAOYSA-N |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | CAY10575 Usage And Synthesis |
| Description | CAY10575 is a benzimidazole analog IKK-ε inhibitor that inhibits IKK-ε with an IC50 value of ~15.8 μM. | | Uses | IKK2-IN-3 (Compound 8) is an IKK2 inhibitor with an IC50 of 0.075 μM[1]. | | Definition | ChEBI: 5-(5,6-dimethoxy-1-benzimidazolyl)-3-[(4-methylsulfonylphenyl)methoxy]-2-thiophenecarboxamide is a member of benzimidazoles. | | IC 50 | IKK2: 0.075 μM (IC50) | | References | [1] Xie HZ, et al. Pharmacophore modeling and hybrid virtual screening for the discovery of novel IκB kinase 2 (IKK2) inhibitors. J Biomol Struct Dyn. 2011 Aug;29(1):165-79. DOI:10.1080/07391102.2011.10507381 |
| | CAY10575 Preparation Products And Raw materials |
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