ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >EthanediaMide iMpurity F

EthanediaMide iMpurity F

EthanediaMide iMpurity F Suppliers list
Company Name: Standardpharm Co. Ltd.
Tel: 86-714-3992388
Email: overseasales1@yongstandards.com
Products Intro: Product Name:Edoxaban Impurity 3
CAS:480452-37-7
Purity:0.99 Package:10mg;25mg;50mg;100mg
Company Name: Dideu Industries Group Limited
Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Products Intro: Product Name:Edoxaban Tosylate
CAS:480452-37-7
Purity:98% Package:25KG Remarks:1097
Company Name: BOC Sciences
Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Products Intro: Product Name:N1-((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide
CAS:480452-37-7
Purity:>=95% Package:100 mg Remarks:Please reach out to us for more information about custom solutions.
Company Name: CR Corporation Limited
Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Products Intro: Product Name:EthanediaMide iMpurity F
CAS:480452-37-7
Company Name: CD Chemical Group Limited
Tel: +8615986615575
Email: info@codchem.com
Products Intro: CAS:480452-37-7
Purity:0.99 Package:1000KG;100KG;5KG;1KG

EthanediaMide iMpurity F manufacturers
EthanediaMide iMpurity F Basic information
Product Name:EthanediaMide iMpurity F
Synonyms:N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxycarbonyl)Amino ]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate;EthanediaMide iMpurity F;N1-{(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl}-N2-(5-chloropyridin-2-yl)ethanediamide;Edoxaban-6;Edoxaban impurity 14/N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxy carbonyl)Amino]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate;Edoxaban iMpurities 6;Ethanediamide, N1-[(1S,2R,4S)-2-amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)-;N1-((1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide (Edoxaban Impurity)
CAS:480452-37-7
MF:C16H22ClN5O3
MW:367.83
EINECS:
Product Categories:
Mol File:480452-37-7.mol
EthanediaMide iMpurity F Structure
EthanediaMide iMpurity F Chemical Properties
density 1.34±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka9.46±0.70(Predicted)
AppearanceWhite to off-white Solid
Safety Information
MSDS Information
EthanediaMide iMpurity F Usage And Synthesis
UsesEdoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2].
References[1] Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9. DOI:10.1111/j.1538-7836.2008.03064.x
[2] Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. DOI:10.1097/FJC.0b013e3182970991
Tag:EthanediaMide iMpurity F(480452-37-7) Related Product Information
2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride edoxaban carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester (1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester 2-Amino-6-chloropyridine EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chlo... (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid 2-Amino-3-chloropyridine