Azido-PEG3-Maleimide

Azido-PEG3-Maleimide Suppliers list

Company Name:	BOC Sciences
Tel:	+1-631-485-4226
Email:	inquiry@bocsci.com
Products Intro:	Product Name:Azido-PEG3-maleimide CAS:1858264-36-4 Purity:>98.0% Remarks:Please reach out to us for more information about custom solutions.

Company Name:	TargetMol Chemicals Inc.
Tel:	+1-781-999-5354; +17819995354
Email:	marketing@targetmol.com
Products Intro:	Product Name:Azido-PEG3-maleimide CAS:1858264-36-4 Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY

Company Name:	Hangzhou Huarong Pharm Co., Ltd.
Tel:	571-86758373 +8613588754946
Email:	sales@huarongpharm.com
Products Intro:	Product Name:Azido-PEG3-maleimide CAS:1858264-36-4 Purity:0.99 Package:10MG,50MG,100MG,1G

Company Name:	Nextpeptide Inc
Tel:	+86-0571-81612335 +8613336028439
Email:	sales@nextpeptide.com
Products Intro:	Product Name:Azido-PEG3-Maleimide CAS:1858264-36-4 Purity:98% Min. Package:5KG;1KG

Company Name:	Hangzhou MolCore BioPharmatech Co.,Ltd.
Tel:	+86-057181025280; +8617767106207
Email:	sales@molcore.com
Products Intro:	Product Name:Azido-PEG3-Maleimide CAS:1858264-36-4 Purity:NLT 98% Remarks:MC457801

Azido-PEG3-Maleimide manufacturers

Azido-PEG3-maleimide
$970.00
2026-04-20
CAS:1858264-36-4
Purity:
Supply Ability: 10g

Azido-PEG3-maleimide
$970.00
2025-09-23
CAS:1858264-36-4
Purity:
Supply Ability: 10g

Azido-PEG3-Maleimide Basic information

Product Name:	Azido-PEG3-Maleimide
Synonyms:	Azido-PEG3-Maleimide;N3-PEG3-Mal;Azide-PEG3-maleimide;Azido-PEG4-BMPA;1H-Pyrrole-1-propanamide, N-[2-[2-[2-(2-azidoethoxy) ethoxy] ethoxy] ethyl]-2,5-dihydro-2,5-dioxo-
CAS:	1858264-36-4
MF:	C15H23N5O6
MW:	369.37302
EINECS:
Product Categories:	peg
Mol File:	1858264-36-4.mol

Azido-PEG3-Maleimide Chemical Properties

Safety Information

MSDS Information

Azido-PEG3-Maleimide Usage And Synthesis

Description

Azido-PEG3-Maleimide is provided as a kit of two vials. Azido-PEG3-Maleimide is not stable for storage; it needs to be made in situ by mixing Azido-PEG3-amine and Maleimide-NHS ester followed by shaking/ stirring for 30 minutes at room temperature. The maleimide group of the Azido-PEG3-Maleimide can react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. Azide group enables Click Chemsitry reactions.

Biological Activity

Azido-PEG3-maleimide is a PROTAC linker belonging to the PEG class, which can be used to synthesize PROTAC molecules. Azido-PEG3-maleimide is also a cleavable ADC linker containing 3-unit PEG, which can be used to synthesize antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

PEGs

Cleavable

Azido-PEG3-Maleimide Preparation Products And Raw materials

Tag:Azido-PEG3-Maleimide(1858264-36-4) Related Product Information

Aminooxy-PEG2-azide Bromo-PEG3-azide Bromoacetamido-PEG4-azido 1-isothiocyanato-PEG3-Azide Azido-PEG5-acid MPEG8-N3 - Aminoxy-PEG3-azide Aminooxy-PEG4-azide PEG-Azide, O-(2-Azidoethyl)-Oμ-methylpolyethylene glycol Azido-PEG7-acid Bromo-PEG4-Azide N3-PEG8-CH2CH2COOH Polyethylene Glycol Azido-PEG12-t-butyl ester Acid-PEG2-t-butyl ester Atorvastatin Epoxy Tetrahydrofuran IMpurity Amino-PEG8-azide

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Azido-PEG3-Maleimide

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