PIPERACILLIN manufacturers
- PIPERACILLIN USP/EP/BP
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- $1.10
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2025-11-18
- CAS:66258-76-2
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
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| | PIPERACILLIN Basic information |
| Product Name: | PIPERACILLIN | | Synonyms: | (2s,5r,6r)-6-[[(2r)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid;Piperacillin (500 mg);Piperacillin (350 mg);Piperacillin CRS;PIPERACILLIN USP/EP/BP;Piperacillin (1541500);2-(4-acetylpiperazin-1-yl)-8-ethyl-5-oxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid (acetylpipemidic acid);Piperacillin RS | | CAS: | 66258-76-2 | | MF: | C23H29N5O8S | | MW: | 535.57 | | EINECS: | 811-368-4 | | Product Categories: | | | Mol File: | 66258-76-2.mol |  |
| | PIPERACILLIN Chemical Properties |
| solubility | Slightly soluble in water, freely soluble in methanol, slightly soluble in ethyl acetate. | | Major Application | pharmaceutical (small molecule) | | InChIKey | NBXPLBPWMYNZTC-IDYPWDAWSA-N | | SMILES | S1[C@H]2N([C@H](C1(C)C)C(=O)O)C(=O)[C@H]2NC(=O)[C@H](NC(=O)N4CCN(C(=O)C4=O)CC)c3ccccc3.O |
| WGK Germany | WGK 3 | | HS Code | 2941106000 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Chronic 3
Skin Sens. 1B |
| | PIPERACILLIN Usage And Synthesis |
| Chemical Properties | White or almost white powder. | | Uses | Penicillin antibacterial. | | in vivo | Piperacillin (100 mg/kg, i.v., 4 times a day, 5 d) hydrate in combination with Tazobactam (HY-B1418)(12.5 mg/kg, i.v., 4 times a day, 5 d) prolongs survival in mice with low inoculum of K. pneumoniae[3].
| Animal Model: | BALB/c low inoculum model of K. pneumoniae, KEN-11 strain[3]. | | Dosage: | 100 mg/kg | | Administration: | Intravenous injection (i.v.), 4 times a day, 5 d, in combination with Tazobactam (12.5 mg/kg, i.v., 4 times a day, 5 d) | | Result: | Enabled all mice survived whereas all control mice died by 5 d, decreased the number of bacteria in lungs compared with control group.
Observed no bacteria in the blood of most mice (except for two mice at the early phase) while bacteria were observed in the blood of control group.
Observed few inflammatory cells in the alveoli whereas an influx of numerous inflammatory cells were observed in the control group.
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| | PIPERACILLIN Preparation Products And Raw materials |
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