| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Aβ42-IN-2
CAS:1914989-80-2
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- manufacturers
- Aβ42-IN-2
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- $35.00
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2026-07-16
- CAS:1914989-80-2
- Purity: 99.87%
- Supply Ability: 10g
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| | 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Basic information |
| | 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Chemical Properties |
| Boiling point | 651.4±55.0 °C(Predicted) | | density | 1.23±0.1 g/cm3(Predicted) | | storage temp. | 4°C, stored under nitrogen | | solubility | DMSO : 20 mg/mL (46.46 mM; Need ultrasonic) | | pka | 4.22±0.10(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Usage And Synthesis |
| Uses | Aβ42-IN-2 (compound example 36) is a γ-secretase modulator. Aβ42-IN-2 has an IC50 of 6.5 nM for Αβ42. Aβ42-IN-2 can be used for the research of Alzheimer's disease[1]. | | Biological Activity | Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for αβ42. Aβ42-IN-2 can be used for the research of Alzheimer’s disease[1]. | | References | [1]. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1. |
| | 3-Pyridazinamine, 6-[6-methoxy-5-(4-methyl-1H-imidazol-1-yl)-2-pyridinyl]-N-[(1S)-1-(4-methoxyphenyl)ethyl]-4-methyl- Preparation Products And Raw materials |
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