| Company Name: |
Shaanxi Dideu Medichem Co. Ltd
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029-81024372 17792795018 |
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1053@dideu.com |
| Products Intro: |
Product Name:acediasulfone sodium
CAS:127-60-6
Purity:99% Package:25kg
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acediasulfone sodium manufacturers
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| | acediasulfone sodium Basic information |
| Product Name: | acediasulfone sodium | | Synonyms: | acediasulfone sodium;N-[4-[(4-Aminophenyl)sulfonyl]phenyl]glycine sodium salt;acediasulfone sodium USP/EP/BP | | CAS: | 127-60-6 | | MF: | C14H15N2NaO4S | | MW: | 330.33 | | EINECS: | 204-852-6 | | Product Categories: | | | Mol File: | 127-60-6.mol |  |
| | acediasulfone sodium Chemical Properties |
| | acediasulfone sodium Usage And Synthesis |
| Originator | Solfone ,Bracco | | Manufacturing Process | 24.8 g of 4,4'-diaminodiphenyl sulfone, 150 g of methyl chloroacetate and 150
ml of ethanol are refluxed together and refluxed for 24 hours. The alcohol and
excess methyl chloroacetate are then distilled off on a steam bath under
reduced pressure. The residue consisting of the hydrochloride salt of 4-amino-
4'-(carbomethoxymethylamino)diphenyl sulfone is mixed with of alcoholic
solution containing 2.5 g lithium hydroxide and refluxed for 4 hours on the
steam bath. Most of the alcohol is removed by distillation and the residual
lithium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone taken up
water. The solution is filtered and dilute HCl added until no more separation
occurs. The 4-amino-4'-(carboxymethylamino)diphenyl sulfone thus obtained
is collected and dried.
The sodium salt of 4-amino-4'-(carboxymethylamino)diphenyl sulfone is
prepared by dissolving the free acid in an aqueous solution containing one
equivalent of sodium hydroxide and evaporating the solution to dryness in
vacuo. | | Therapeutic Function | Antibacterial |
| | acediasulfone sodium Preparation Products And Raw materials |
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