CBP/P300-IN-14
| 中文名稱 | CBP/P300-IN-14 |
|---|---|
| 中文同義詞 | |
| 英文名稱 | 3-Isoquinolinecarboxamide, 1-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-N-methyl-6-(4-methyl-2-oxo-1-piperazinyl)- |
| 英文同義詞 | 3-Isoquinolinecarboxamide, 1-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-N-methyl-6-(4-methyl-2-oxo-1-piperazinyl)-;CBP/p300-IN-14 |
| CAS號 | 2725036-10-0 |
| 分子式 | C30H31F2N7O2 |
| 分子量 | 559.61 |
| EINECS號 | |
| 相關(guān)類別 | |
| Mol文件 | 2725036-10-0.mol |
| 結(jié)構(gòu)式 |  |
CBP/P300-IN-14 性質(zhì)
| 沸點(diǎn) | 880.3±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.40±0.1 g/cm3(Predicted) |
| 酸度系數(shù)(pKa) | 12.51±0.46(Predicted) |
CBP/p300-IN-14 是一種有效的 CBP/EP300 (賴氨酸乙酰轉(zhuǎn)移酶) 抑制劑，IC50 值為 3.3 nM (提取自專利 WO2021213521A1，compound 27)。