Product Details
| Product Name: Adapalene | CAS No.: 106685-40-9 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2026/07/03 |
| Lead time: In stock, ready for shipment | In stock, r: bag/bottle/drum/IBC |
| COA, MSDS: Available, contact us for details | Origin: Manufacturer, advantage product |
| Delivery : By express, by air, by sea | NAME: Sun |
1. Materials information
| Name | adapalene |
|---|---|
| Synonym | More Synonyms |
| Description | Adapalene(CD-271; Differin), a synthetic retinoid, is a retinoic acid receptor agonist (RAR).Target: Retinoic acid receptor agonist (RAR)Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. Adapalene is possibly more effective than tretinoin 0.025% gel in the treatment of acne vulgaris [1].Thirty-six rats of either sex were divided into six groups (two control groups, and an etodolac, indomethacin, tretinoin and adapalene group) of six animals each. Each group was given different drugs or chemicals. The inhibitory activities of the drugs were determined on carrageenan-induced rat-paw oedema. The inhibition rate (53.48%) in the tretinoin group was found to be higher thanadapalene and controls (P < 0.05). Adapalene was found to have an inhibition rate of 10.28%, and when compared with the other groups, was found to have no statistically significant anti-inflammatory activity [2]. |
|---|---|
| Related Catalog | Signaling Pathways >> Metabolic Enzyme/Protease >> RAR/RXR Research Areas >> Inflammation/Immunology |
| References | [1]. Ellis CN, et al. Comparison of adapalene 0.1% solution and tretinoin 0.025% gel in the topical treatment of acne vulgaris. Br J Dermatol. 1998 Oct;139 Suppl 52:41-7. [2]. Akdeniz N, et al. Anti-inflammatory effects of tretinoin (all-trans-retinoic acid) 0.1% and adapalene 0.1% in rats. Clin Exp Dermatol. 2005 Sep;30(5):570-2. |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 606.3±55.0 °C at 760 mmHg |
| Melting Point | 319-322oC |
| Molecular Formula | C28H28O3 |
| Molecular Weight | 412.520 |
| Flash Point | 205.9±25.0 °C |
| Exact Mass | 412.203857 |
| PSA | 46.53000 |
| LogP | 8.04 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.655 |
| Storage condition | Store at +4°C |
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/LINE: 8613526505137
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