α-MSH TFA NEW
| Price | $72 | $258 | $475 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-01-05 |
Product Details
| Product Name: α-MSH TFA | CAS No.: 171869-93-5 |
| Supply Ability: 10g | Release date: 2026/01/05 |
Product Introduction
Bioactivity
| Name | α-MSH TFA |
| Description | α-Melanocyte-stimulating hormone (α-MSH) is a 13-amino acid peptide hormone produced by post-translational processing of proopiomelanocortin (POMC) in the pituitary gland, as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.1It is an agonist of melanocortin receptor 3 (MC3R) and MC4R that induces cAMP production in Hepa cells expressing the human receptors (EC50s = 0.16 and 56 nM, respectively).2α-MSH (100 pM) reducesS. aureuscolony formation andC. albicansgerm tube formationin vitro.3It inhibits endotoxin-, ceramide-, TNF-α-, or okadaic acid-induced activation of NF-κB in U937 cells.1α-MSH reduces IL-6- or TNF-α-induced ear edema in mice.4It also prevents the development of adjuvant-induced arthritis in rats and increases survival in a mouse model of septic shock. Increased plasma levels of α-MSH are positively correlated with delayed disease progression and reduced death in patients with HIV.1 |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMF : 10 mg/mL (5.62 mM), Sonication is recommended. DMSO : 25 mg/mL (14.05 mM), Sonication is recommended. DMSO:PBS (pH 7.2) (1:5) : 0.16 mg/mL (0.09 mM), Sonication is recommended. |
| Keywords | α-MSH TFA | αMSH TFA | α MSH TFA | a-MSH TFA | alpha-MSH TFA |
| Inhibitors Related | (±)-Eriodictyol | α-MSH | Setmelanotide | 4-Methyl-6-Methoxycoumarin | Fenoprofen Calcium | α-MSH acetate | Afamelanotide acetate | BMS-470539 dihydrochloride | ACTH (1-17) acetate | Tetracosactide acetate | [D-Trp8]-γ-MSH acetate(321351-81-9 free base) | Undecylenoyl phenylalanine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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