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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Epigenetics>Histone Methyltransferase Inhibitors>UNC 0631
UNC 0631
  • UNC 0631
  • UNC 0631
  • UNC 0631

UNC 0631

Price $0.01
Package 1KG
Min. Order: 1KG
Supply Ability: 1kg; 5kg; 10kg
Update Time: 2024-10-22

Product Details

Product Name: UNC 0631 CAS No.: 1320288-19-4
Min. Order: 1KG Purity: 95%-99%
Supply Ability: 1kg; 5kg; 10kg Release date: 2024/10/22
product number: 604Crystal
Product Name: UNC 0631
Synonyms: UNC 0631, >=98%;N-(1-(cyclohexylmethyl)piperidin-4- yl)-2-(4-isopropyl-1,4-diazepan-1-yl)- 6-methoxy-7-(3-(piperidin-1- yl)propoxy)quinazolin-4-amine;N-[1-(Cyclohexylmethyl)-4-piperidinyl]-2-(4-isopropyl-1,4-diazepa n-1-yl)-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine;UNC 0631;UNC0631/UNC-0631;N-[1-(CyclohexylMethyl)-4-piperidinyl]-2-[hexahydro-4-(1-Methylethyl)-1H-1,4-diazepin-1-yl]-6-Methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinaMine;N-[1-(Cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine UNC0631;CS-793
CAS: 1320288-19-4
MF: C37H61N7O2
MW: 635.92594
EINECS:  
Product Categories: Inhibitors;Amines, Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Mol File: 1320288-19-4.mol
Article illustration
 
UNC 0631 Chemical Properties
Boiling point  763.4±70.0 °C(Predicted)
density  1.114±0.06 g/cm3(Predicted)
pka 9.34±0.70(Predicted)
 
Safety Information
MSDS Information
 
 
UNC 0631 Usage And Synthesis
Uses N-[1-(Cyclohexylmethyl)-4-piperidinyl]-2-[hexahydro-4-(1-methylethyl)-1H-1,4-diazepin-1-yl]-6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinamine, is a selective histone lysine methyltransferase (HMTase) inhibitor for G9a and GLP.
Uses UNC0631 is a potent and selective inhibitor of G9a activity in vitro (IC50 = 4 nM) and G9a/GLP-mediated dimethylation of histone 3 on lysine 9 in MDA-MB-231 cells (IC50 = 25 nM). It potently inhibits G9a/GLP activity in a variety of cancer cell lines as well as in the human fetal lung IMR-90 cell line.[Cayman Chemical]

Company Profile Introduction

Technology research and transfer of pilot screening, pilot scale-up and mass production solutions , for pharmaceutical intermediates, biologicals and fine chemicals (Not including inflammable , explosive , hazardous goods ) ; Market : Nano material , metal catalyst , raw material of cosmetics , pharmaceutical intermediates , chemicals , photoelectric material , import and export of technology and goods (For projects subject to approval according to law, business activities can be carried out only after approval by relevant departments ).

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