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Postion:Product Catalog >Myostain GDF 8
Myostain GDF 8
  • Myostain GDF 8

Myostain GDF 8

Price $230
Package 1BOX
Min. Order: 50BOX
Supply Ability: 5
Update Time: 2020-12-09

Product Details

Product Name: Myostain GDF 8 CAS No.: 901758-09-6
Min. Order: 50BOX Purity: 99%
Supply Ability: 5 Release date: 2020/12/09

Description of GDF-8

 

Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.
Animals either lacking myostatin or treated with substances that block the activity of myostatin have significantly more muscle mass. Furthermore, individuals who have mutations in both copies of the myostatin gene have significantly more muscle mass and are stronger than normal. Blocking the activity of myostatin may have therapeutic application in treating muscle wasting diseases such as muscular dystrophy.

 

 

Product NameTop quality GDF-8
Brand NameSIGMA
Packing1box/10vials,1mg/vial
CAS No901758-09-6
Molecular FormulaC221H366N72O67S
ApplicationPharmaceutical raw materials
purity> 99.0%

 

Usage of GDF-8

 

The gene encoding myostatin was discovered in 1997 by geneticists Se-Jin Lee and Alexandra McPherron who produced a strain of mutant mice that lack the gene. These myostatin "knockout" mice have approximately twice as much muscle as normal mice. These mice were subsequently named "mighty mice".
Naturally occurring deficiencies of myostatin have been identified in cattle by Ravi Kambadur, whippets, and humans; in each case the result is a dramatic increase in muscle mass. A mutation in the 3' UTR of the myostatin gene in Texel sheep creates target sites for the microRNAs miR-1 and miR-206. This is likely to cause the muscular phenotype of this breed of sheep.

 

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Company Profile Introduction

Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places.

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