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Postion:Product Catalog >Chemical Reagents>Organic reagents>Thiol / thiol>DTT/DL-Dithiothreitol
DTT/DL-Dithiothreitol
  • DTT/DL-Dithiothreitol

DTT/DL-Dithiothreitol

Price $3
Package 1g
Min. Order: 100KG
Supply Ability: 100
Update Time: 2020-12-16

Product Details

Product Name: DTT/DL-Dithiothreitol CAS No.: 27565-41-9
Min. Order: 100KG Purity: 99%
Supply Ability: 100 Release date: 2020/12/16

SPECIFICATION


Product Name:  DTT; DL-1,4-Dithiothreitol; DITHIOTHREITOL 
 Cas:  3483-12-3 /27565-41-9
 Formula:  C4H10O2S2 
 Appearance:  White crystal
 Assay:  ≥99%


1. DL-1,4-Dithiothreitol  is as a reducing agent and deprotecting agent for thiolated DNA. The thiolated DNA terminal sulfur atom tends to form a dimer in solution, especially in the presence of oxygen. This dimerization greatly reduces the efficiency of some coupling reaction experiments (such as the immobilization of DNA in biosensors); while adding DTT to the DNA solution and removing it after a period of reaction, the dimerization of DNA can be reduced.

2. DL-1,4-Dithiothreitol is also often used for the reduction of disulfide bonds in proteins and can be used to prevent intramolecular or intermolecular disulfide bonds of proteins formed between cysteines in proteins. However, DTT often cannot reduce the disulfide bonds embedded in the protein structure (solvent unreachable). The reduction of such disulfide bonds often requires denaturation of the protein (heating at high temperature or adding a denaturing agent such as 6M guanidine hydrochloride, 8M urea or 1% SDS). On the contrary, according to the difference in the rate of reduction of disulfide bonds in the presence of DTT, the degree of embedding can be judged.

3.DL-1,4-Dithiothreitol Packaging and Shipping.


Company Profile Introduction

Our company is a professional in lead acetate, diphenyl ethylamine and other chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places.

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