Product Details
| Product Name: Polymyxin B sulfate | CAS No.: 1405-20-5 |
| Min. Order: 10g | Purity: 99% |
| Supply Ability: 1000KG | Release date: 2021/11/02 |
| Melting point | 217-220°C (dec.) |
| storage temp. | 2-8°C |
| solubility | H2O: 50 mg/mL |
| form | powder |
| pka | pKa 8.9 (Uncertain) |
| color | colorless or slightly yellow |
| PH | pH (10g/L, 25℃) : 4.5～7.0 |
| optical activity | [α]/D 20/D (Rotation: -2.3 +/- 0.2 degrees) |
| Water Solubility | Soluble in water at 50mg/ml/n |
| Merck | 14,7573 |
| CAS DataBase Reference | 1405-20-5(CAS DataBase Reference) |
| EPA Substance Registry System | Polymixin B sulfate (1405-20-5) |
| Uses | Biochemical studies. Polymyxin B is a kind of anti-Gram-negative poly-peptide antibiotics which can alter membrane structure allowing small molecules leakage and inhibit the growth of Gram-negative bacteria. It has bactericidal effect on Escherichia coli through binding to the lipid A portion of bacterial lipopolysaccharide. Mechanism of action: bind and interfere with the permeability o the cellular membrane. Anti-bacteria spectrum: gram negative bacteria. |
| Chemical Properties | White Solid |
| Uses | antibacterial |
| Uses | Antibiotic with bactericidal action on E. coli. Binds to the lipid A portion of bacterial lipopolysaccharides. Induces pore formation in the membranes of cortex cells from excised sorghum roots. Mixtu re of Polymyxin B1 and B2 sulfate. Biological potency (dry basis): >6000U/mg. |
| Uses | Polymyxin B sulfate is used as topical antibiotic agent, often used in combination with neomycin; products include ointments, creams, eye, and ear drops. |
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China- Since: 2018-09-06
- Address: Room B801, Financial Plaza, Jintai District, Baoji, Shaanxi, CN
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