1,4-DPCA NEW
| Price | $47 | $76 | $155 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: 1,4-DPCA | CAS No.: 331830-20-7 |
| Purity: 97.77% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | 1,4-DPCA |
| Description | 1,4-DPCA is an inhibitor of prolyl-hydroxylase with an IC50 of 2.4 μM for collagen hydroxylation in human foreskin fibroblasts and 60 μM for factor inhibiting HIF (FIH). |
| In vitro | 1,4-DPCA significantly reduces the colony sizes and invasive branches of T4-2 (10 μM) and ZR-75-1 cells (20 μM). 1,4-DPCA inhibits the proliferation in T4-2, ZR-75-1, MDA-MB-231 cells, and MDA-MB-157[1]. In mouse B6 cells, 1,4-DPCA specifically increases the expression of proangiogenic target genes including Hmox1 and Vegfa, and proglycolytic targets including Ldh-a, Pdk1, Glut1, and Pgk1[2]. |
| In vivo | In mice, 1,4-DPCA effectively inhibits collagen deposition within and on the outer surface of the disc, and limits connective tissue ingrowth. 1,4-DPCA suppresses connective tissue ingrowth in porous porous poly (lactic-co-glycolic acid) discs implanted in the peritoneal cavity[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 1.54 mg/mL (6.41 mM), Sonication is recommended. 10% DMSO+90% Saline : 0.15 mg/mL (0.62 mM), Solution. |
| Keywords | wound | P4HA3 | P4HA2 | P4HA1 | Inhibitor | inhibit | Hypoxia-inducible factors | HIFs | HIFProlylHydroxylase | HIF-PH | HIF-1α | HIF/HIFProlylHydroxylase | HIF/HIF Prolyl-Hydroxylase | HIF/HIF ProlylHydroxylase | HIF Prolyl-Hydroxylase | HIF ProlylHydroxylase | HIF | healing | FIH | 1,4-DPCA | 1,4DPCA | 1,4 DPCA |
| Inhibitors Related | Deferoxamine Mesylate | Hydralazine hydrochloride | Chlorogenic Acid | Roxadustat | Glucosamine | Hydroxycitric acid tripotassium hydrate | Glucosamine hydrochloride | Chloramphenicol | Oroxylin A | Acriflavine Hydrochloride | Albendazole | Glucosamine sulfate |
| Related Compound Libraries | Glycolysis Compound Library | Glycometabolism Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Glutamine Metabolism Compound Library | Hematonosis Compound Library | Anti-Cancer Metabolism Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Metabolism Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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