14,15-Leukotriene E4 NEW
| Price | $478 |
| Package | 25μg |
| Supply Ability: | 10g |
| Update Time: | 2025-12-22 |
Product Details
| Product Name: 14,15-Leukotriene E4 | CAS No.: 1000852-57-2 |
| Supply Ability: 10g | Release date: 2025/12/22 |
Product Introduction
Bioactivity
| Name | 14,15-Leukotriene E4 |
| Description | Leukotrienes (LTs) are a group of acute inflammatory mediators derived from arachidonic acid in leukocytes. The majority of these metabolites are formed through the 5-lipoxygenase (5-LO) pathway. 14,15-LTE4 is a metabolite of 14,15-LTC4 and 14,15-LTD4, an alternate class of LTs synthesized by a pathway involving the dual actions of 15- and 12-LOs on arachidonic acid via 15-HpETE and 14,15-LTA4 intermediates. These metabolites are classified as eoxins because they are formed mostly by eosinophils. Mast cells and nasal polyps can synthesize 14,15-LTC4 as well, however metabolism to 14,15-LTE4 in these cells and tissue has not been documented. 14,15-LTE4 increases vascular permeability of human endothelial cell monolayers with about 10-fold less potency than LTC4, but approximately 100-fold greater potency than histamine. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : > 50 mg/mL, Sonication is recommended. DMF : > 50 mg/mL, Sonication is recommended. DMSO : > 50 mg/mL, Sonication is recommended. PBS (pH 7.2) : > 100μg/mL, Sonication is recommended. |
| Keywords | 14,15Leukotriene E4 | 14,15 Leukotriene E4 | 14,15-Leukotriene E-4 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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