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Postion:Product Catalog >API>Antiallergic drugs>Antihistamines>Chlorpheniramine maleate
Chlorpheniramine maleate
  • Chlorpheniramine maleate
  • Chlorpheniramine maleate
  • Chlorpheniramine maleate
  • Chlorpheniramine maleate
  • Chlorpheniramine maleate

Chlorpheniramine maleate

Price $40
Package 1KG
Min. Order: 1KG
Supply Ability: 10 tons
Update Time: 2021-08-12

Product Details

Product Name: Chlorpheniramine maleate CAS No.: 113-92-8
EC-No.: 204-037-5 Min. Order: 1KG
Purity: 99 Supply Ability: 10 tons
Release date: 2021/08/12

Product Name:

Chlorpheniramine maleate

Molecular weight:

390.8606

Appearance: 

White Crystals Powder

Molecular Formula

C20H23ClN2O4

CAS 

113-92-8Boiling point579.3°C at 760 mmHg
EINECS204-037-5Melting point130-135oC
Flash point304.2°CWater solubility1-5 g/100 mL at 21oC
MOQ1KGShelf Life2 Years

Chlorpheniramine Maleate is a small molecule H1-receptor antagonist. Increased ornithine decarboxylase activity induced in an is chemia-reperfusion state was attenuated by Chlorpheniramine Maleate, indicating that this increase is mediated through engagement of the H1-receptor by histamine. Histamine-mediated repair of intestinal mucosa following ischemia-reperfusion was also demonstrated to operate through the H1-receptor with Chlorpheniramine Maleate. Induction of ornithine decarboxylase was blocked by Chlorpheniramine Maleate in Ehrlich carcinoma and MCF-7 cells. The positive inotropic effect of H1-receptor stimulation by histamine on protein tyrosine phosphorylation in guinea pig left atrium was antagonized by Chlorpheniramine Maleate.


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