Product Details
| Product Name: Coenzyme II reduced tetrasodium salt(NADPH) | CAS No.: 2646-71-1 |
| EC-No.: 220-163-3 | Min. Order: 25mg |
| Purity: 95% | Supply Ability: 10tons |
| Release date: 2023/07/19 |
Coenzyme II reduced tetrasodium salt
CAS 2646-71-1
PROPERTIES
Product name | Coenzyme II reduced tetrasodium salt |
Abbreviation | NADPH |
Alias | β-NADPH, NADPH Na4, Dihydronicotinamide adenine dinucleotide phosphate, 2' -NADPH hydrate, Coenzyme II reduced tetrasodium salt, Triphosphopyridine nucleotide reduced tetrasodium salt ,TPNH2 Na4 |
Molecular formula | C21H26N7O17P3·Na4 or C21H26N7Na4O17P3 |
Molecular weight | 833.35 |
CAS number | 2646-71-1 |
Purity | 95% |
Appearance | White to light yellow lyophilized powder |
Maximum absorbance | 260nm and 340nm |
Solubility | Soluble in water (50 mg/ml).10 mM NaOH: soluble 50 mg/mL, clear |
Description
Application
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).
β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt has been used in the Griess reagent assay of culture medium to reduce nitrate to nitrite and in glutathione peroxidase assay.
Biochem/physiol Actions
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivo by the pentose phosphate pathway (PPP).
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